SI
Imperial
General Calculators
BMI and BSA (Mosteller)
Calculate BMI and Body Surface Area using Mosteller formula
BMI and BSA (Du Bois)
Determine body mass index and body surface area using Du Bois method
Ideal Body Weight
Weight-based medication dosing
Adjust medication dose based on patient weight
Body Surface Area Based Dosing
Medication dose adjustment based on body surface area (BSA)
Lean Body Weight (Female)
Calculates estimated patient fat-free body mass in females
Lean Body Weight (Male)
Calculates estimated patient fat-free body mass in males
Addiction Medicine
Alcohol Use Disorders Identification Test-Concise (AUDIT-C)
Brief screen to detecting heavy alcohol use
Alcohol Use Disorders Identification Test (AUDIT)
Screen for active alcohol abuse or dependence
CAGE Questionnaire
4 question screening for alcohol problems
Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT 2.1)
9 question screener for substance use in adolescents
COWS Score for Opiate Withdrawal
Post Traumatic Stress Disorder (PCL-C)
17 question self-report for Post Traumatic Stress Disorder
Adverse Childhood Experience (ACE)
10 question screener for numerous health, social, and behavioral problems.
Anesthesiology
Airway & Respiratory
Pediatric Endotracheal Tube Size
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
STOP-BANG Score for Obstructive Sleep Apnea
Screen for obstructive sleep apnea
Modified Mallampati Classification
Oropharyngeal assessment used for predicting difficulty in laryngoscopy and endotracheal intubation
Recruitment to Inflation Ratio
Characterize lung recruitability to personalize PEEP. Adapted from an algorithm developed by The Toronto Centre of Excellence in Mechanical Ventilation (CoEMV).
BMI
BMI and BSA (Mosteller)
Calculate BMI and Body Surface Area using Mosteller formula
BMI and BSA (Du Bois)
Determine body mass index and body surface area using Du Bois method
Cardiac Surgery
Dialysis Risk After Cardiac Surgery (Cleveland Clinic Score by Thakar)
Estimate risk of dialysis after cardiac surgery.
Dialysis Risk After Cardiac Surgery (Mehta)
Estimate the risk of dialysis after cardiac surgery (Mehta model)
PORT score for PeriOperative Risk of blood Transfusion in cardiac surgery by ACTA
Predict risk of blood transfusion after elective cardiac surgery using the ACTA-PORT score
Clinical Status Assessment
APACHE II
Estimate mortality in the critically ill
Glasgow Coma Scale (GCS)
Document level of consciousness.
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
qSOFA Score in Septic Patients
Predict patients at high-mortality risk from sepsis (not diagnose sepsis)
Intraoperative Monitoring
Cardiac Output - Fick
Calculate cardiac output, cardiac index, stroke volume and stroke volume index
Obstetrical Anesthesia
Due Date by LMP
Pregnancy due date calculator
Due Date by Ultrasound
Determine pregnancy due date using ultrasound results
Pregnancy Gestation by LMP and Ultrasound Biometry
Predicts estimated delivery dates and gestational age using LMP and biometry
Pre-operative Assessment
ARISCAT Score
Risk calculator for postoperative pulmonary complications
Preoperative Assessment
ACC/AHA CV Risk Calculator (2013)
Estimate 10-year risk for atherosclerotic cardiovascular disease
Revised Cardiac Risk Index (Lee Criteria)
Rapid pre-op assessment using the Revised Cardiac Risk Index
Asymptomatic ICA (Internal Carotid Artery) Stenosis Surgical Risk Stratification
Gupta Perioperative Cardiac Risk
Determine peri-operative risk for a wide variety of surgeries
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
VSGNE Ruptured Abdominal Aortic Aneurysm (RAAA) Risk Score
Estimate mortality after open repair of ruptured AAA
Pre-test probability of CAD (CAD consortium)
Determine pre-test probability of coronary artery disease in patients with chest pain.
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Carotid Endarterectomy
Estimate risk of post-op myocardial infarction after carotid endarterectomy
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | EVAR
Estimate risk of post-op myocardial infarction after EVAR
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Infra-inguinal Bypass
Estimate risk of post-op myocardial infarction after infra-inguinal bypass
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Open AAA Repair
Estimate risk of post-op myocardial infarction after open AAA repair
VQI: Respiratory Adverse Event Risk Post Vascular Surgery
Estimate the risk of pneumonia or respiratory failure after vascular surgery
Vascular Quality Initiative (VQI) 30-Day Stroke Risk Index for CEA
Estimate risk of stroke within 30 days after carotid endarterectomy
Vascular Quality Initiative (VQI) 1-Year Mortality Risk Index for CEA
Estimate probability of death within 1 year after carotid endarterectomy
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Suprainguinal Bypass
Estimate risk of post-op myocardial infarction after suprainguinal bypass
Geriatric-Sensitive Perioperative Cardiac Risk Index | GSCRI
Estimate risk of perioperative myocardial infarction or cardiac arrest in patients over 65
ASA Physical Status
Classification system for assessing the fitness of patients before surgery
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
VISION perioperative risk using NT-proBNP
Predict risk of MI, vascular death, and all-cause death in patients having non-cardiac surgery
COVID-19
ROX Index to Predict Risk of Intubation
Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19
COVID-19 Prognostic Tool
Estimate mortality rates in patients with COVID-19. Adapted from CDC materials.
COVID-19 Ventilation Protocol
Adapted from an algorithm developed by The Toronto Centre of Excellence in Mechanical Ventilation (CoEMV)
COVID-19 Critical Illness Prediction Tool (COVID-GRAM)
Predict occurrence of ICU admission, mechanical ventilation, or death in hospitalized patients with COVID-19
REFERENCE BOOK
Guidance on Autopsy in COVID-19 with FAQ
What Are the Appropriate Collection Procedures If an Autopsy Is Performed for a Suspected Coronavirus Disease 2019 (COVID-19) Case?
What Are the Appropriate Collection Procedures If an Autopsy Is Not Performed for a Suspected Coronavirus Disease 2019 (COVID-19) Case?
What Are the Appropriate Collection Procedures If an Autopsy Is Performed for a Confirmed Coronavirus Disease 2019 (COVID-19) Case?
What Are the Personal Protective Equipment Recommendations for Autopsies on Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) Decedents?
What General Precautions Should Be Taken When Performing an Autopsy on Coronavirus Disease 2019 (COVID-19) Decedents?
What Are Recommended Collection Procedures for Coronavirus Disease 2019 (COVID-19) Postmortem Specimens?
What Are Recommended Practices for Transportation of Human Remains for Coronavirus Disease 2019 (COVID-19) Decedents?
References
REFERENCE BOOK
COVID-19: Triage, Diagnosis and Management
Symptoms and Management of Coronavirus Disease 2019 (COVID-19) FAQ
What are the signs and symptoms of coronavirus disease 2019 (COVID-19)?
What are the signs and symptoms of severe or critical coronavirus disease 2019 (COVID-19)?
How is mild coronavirus disease 2019 (COVID-19) managed?
Who is at risk for severe coronavirus disease 2019 (COVID-19)?
How is severe or critical coronavirus disease 2019 (COVID-19) managed?
How is acute respiratory distress syndrome (ARDS) managed in patients with critical coronavirus disease 2019 (COVID-19)?
How are acute cardiac complications managed in patients with coronavirus disease 2019 (COVID-19)?
Which drugs are effective for the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of the antiviral drug remdesivir in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of the antivirals lopinavir/ritonavir in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of the antiviral drug rintatolimod in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of the antiviral drug plitidepsin in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of the antiviral drug favipiravir in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of interleukin-6 (IL-6) inhibitors in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of hydroxychloroquine and chloroquine in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of azithromycin in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of corticosteroids (such as methylprednisolone) in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of convalescent plasma in the treatment of coronavirus disease 2019 (COVID-19)?
What is the status of nitric oxide in the treatment of coronavirus disease 2019 (COVID-19)?
References
Diagnostics for Coronavirus Disease 2019 (COVID-19) Patients
What is the incubation period for coronavirus disease 2019 (COVID-19)?
What are complications of patients with coronavirus disease 2019 (COVID-19)?
Medscape COVID-19 Resources
References
What is the range of illness severity of patients with coronavirus disease 2019 (COVID-19)?
What are the signs and symptoms of patients with coronavirus disease 2019 (COVID-19)?
What is known about asymptomatic and presymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?
What is known about asymptomatic and presymptomatic transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?
What is the clinical progression of patients with coronavirus disease 2019 (COVID-19)?
What are risk factors for severe illness in patients with coronavirus disease 2019 (COVID-19)?
What data are available about reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?
Are patients with coronavirus disease 2019 (COVID-19) at risk for hypercoagulability?
What are common laboratory findings in patients with coronavirus disease 2019 (COVID-19)?
What are common radiologic findings in patients with coronavirus disease 2019 (COVID-19)?
What diagnostic test is used to detect coronavirus disease 2019 (COVID-19)?
Is antibody testing recommended for diagnosing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection?
What are the patient categories for viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?
What testing is recommended for persons with signs or symptoms consistent with coronavirus disease 2019 (COVID-19)?
What testing is recommended for asymptomatic individuals with known or suspected exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to control transmission?
What testing is recommended for asymptomatic individuals without known or suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure for early identification in special settings?
What testing is recommended to determine resolution of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)?
What does public health surveillance for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) involve?
What is the testing procedure for coronavirus disease 2019 (COVID-19)?
What are general guidelines for specimens of patients with coronavirus disease 2019 (COVID-19)?
Coronavirus Disease 2019 (COVID-19) Triage Precautions FAQ
What are the first steps for patients presenting with suspected coronavirus disease 2019 (COVID-19)?
What precautions should be taken by healthcare providers regarding coronavirus disease 2019 (COVID-19) patients?
What precautions should be taken when performing procedures on coronavirus disease 2019 (COVID-19) patients?
References
Cardiac Surgery
Surgery in Asymptomatic Aortic Stenosis
Assess timing of surgery in severe, asymptomatic aortic stenosis
BC Cardiac Surgical Intensive Care Score
Predict mortality after cardiac surgery based on preoperative and intraoperative variables assessed at admission to a cardiac surgery ICU
Dialysis Risk After Cardiac Surgery (Cleveland Clinic Score by Thakar)
Estimate risk of dialysis after cardiac surgery.
Dialysis Risk After Cardiac Surgery (Mehta)
Estimate the risk of dialysis after cardiac surgery (Mehta model)
HIT 4T's score
Diagnose heparin-induced thrombocytopenia.
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
Euroscore II
Estimate risk of in-hospital death after cardiac surgery.
Aortic Stenosis Risk Score
Estimate risk of cardiovascular events in patients with aortic stenosis
PORT score for PeriOperative Risk of blood Transfusion in cardiac surgery by ACTA
Predict risk of blood transfusion after elective cardiac surgery using the ACTA-PORT score
ADviSED - Aortic Dissection Detection Risk Score Plus D-Dimer for Aortic Syndromes
Rule out aortic dissection and other aortic syndromes
Predicted Heart Mass Calculator (PHM)
Estimate donor/recipient heart mass for optimal cardiac transplant sizing
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Cardiology
Aortic Disease
ADviSED - Aortic Dissection Detection Risk Score Plus D-Dimer for Aortic Syndromes
Rule out aortic dissection and other aortic syndromes
Aortic Stenosis/Outflow
AS: Aortic Valve Area (Cont)
Estimate aortic valve area
AS: Aortic Valve Area (DVI)
Estimate aortic valve area
AS: Aortic Valve Area (Gorlin)
Estimate aortic valve area
AS: Aortic Valve Area (Hakki)
Estimate aortic valve area
Surgery in Asymptomatic Aortic Stenosis
Assess timing of surgery in severe, asymptomatic aortic stenosis
Aortic Stenosis Risk Score
Estimate risk of cardiovascular events in patients with aortic stenosis
HCM Risk-SCD
Assess risk of sudden cardiac death and need for ICD in hypertrophic cardiomyopathy
Arrhythmia
Brugada Criteria for Ventricular Tachycardia
ECG criteria to help differentiate ventricular tachycardia from supraventricular tachycardia.
Atrial Fibrillation
Bleeding Risk in Atrial Fibrillation: OBRI
The Outpatient Bleeding Risk Index (OBRI) estimates risk of bleeding in AF while on oral anticoagulation.
CHADS2 Score for Atrial Fibrillation
Assess risk of stroke in atrial fibrillation
CHA2DS2-VASc Score for AF
Replacement for CHADS2 for stroke prediction in atrial fibrillation
Bleeding Risk in Atrial Fibrillation: HAS-BLED Score
Understand the risk of bleeding from anticoagulation in atrial fibrillation
Warfarin Bleeding Risk - Elderly
Estimate 90 day risk of bleeding in patients on warfarin who are >65 years
Bleeding Risk in Atrial Fibrillation: ATRIA
Estimate bleeding risk for patients on warfarin.
GARFIELD-AF Risk Calculator
Compare the effects of different anticoagulant treatment decisions in atrial fibrillation
CCS-SAF Symptom Score
Canadian Cardiovascular Society (CCS) Severity of Atrial Fibrillation (SAF) scale describes severity of symptoms in atrial fibrillation.
Bleeding Risk
Bleeding Risk in Atrial Fibrillation: OBRI
The Outpatient Bleeding Risk Index (OBRI) estimates risk of bleeding in AF while on oral anticoagulation.
CRUSADE Score for Post-MI Bleeding Risk
Estimate bleeding risk after NSTEMI.
Bleeding Risk in Atrial Fibrillation: HAS-BLED Score
Understand the risk of bleeding from anticoagulation in atrial fibrillation
Warfarin Bleeding Risk - Elderly
Estimate 90 day risk of bleeding in patients on warfarin who are >65 years
GARFIELD-AF Risk Calculator
Compare the effects of different anticoagulant treatment decisions in atrial fibrillation
Coronary Artery Disease
Infarct Size - Anterior
Estimate infarct size in anterior MI
Infarct Size - Inferior
Estimate infarct size in inferior MI
HEART Score | Chest pain in the ER
Risk stratify patients with chest pain in the ER
Killip Class
Estimate mortality in myocardial infarction
TIMI Risk Score (NSTEMI)
Guide therapeutic decisions in non-ST elevation MI.
Reynolds CAD Risk
TIMI Risk Score (STEMI)
VALIANT Heart Failure Risk Score
GRACE
The GRACE ACS risk calculator estimates risk of death following acute coronary syndrome (ACS)
Pre-test probability of CAD (CAD consortium)
Determine pre-test probability of coronary artery disease in patients with chest pain.
Sgarbossa’s Criteria for MI in Left Bundle Branch Block
Allows for the diagnosis of acute MI in patients with known LBBB
CCS Angina Class
Universal Definition of MI
ECG
ECG: Heart Rate
ECG: Corrected QT
Calculate the corrected QT interval
ECG: Cycle Length
Echocardiography
AR: Quantification (Volumetric)
AR: Regurgitant Orifice (PISA)
Measure effective regurgitant orifice by PISA
AS: Aortic Valve Area (Cont)
Estimate aortic valve area
AS: Aortic Valve Area (DVI)
Estimate aortic valve area
Ejection Fraction (Simplified)
Fractional Shortening
Hemodynamics (Echo)
Left Atrial Systolic Pressure
LV/RV Contractility (dp/dt)
Modified Bernoulli Equation
MR: Quantification (PISA)
MR: Quantification (Volumetric)
MS: Wilkins' Echo Score
MS: Mitral Valve Area (Cont)
MS: Mitral Valve Area (PHT)
MS: Mitral Valve Area (PISA)
Myocardial Performance Index (CO and ET)
Myocardial Performance Index (IVRT and IVCT)
PCWP (Echo)
RV Systolic Pressure (TR Jet)
Shunt Fraction (Echo)
Familial Hypercholesterolemia
Familial Hypercholesterolemia
Diagnose familial hypercholesterolemia
Frailty
MDS Specific Frailty Scale
Improve prognostication with this frailty scale specific to those patients with myelodysplastic syndrome.
Heart Failure
Framingham CHF Criteria
Forrester HF Class
Killip Class
Estimate mortality in myocardial infarction
Seattle Heart Failure Model
Stevenson HF Class
VALIANT Heart Failure Risk Score
Emergency Heart Failure Mortality Risk Grade (EHMRG)
Risk stratify patients with acutely decompensated heart failure
Optimize Care in Heart Failure with Reduced Ejection Fraction
Workup, treatment & management for heart failure
Sponsored
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
NYHA Functional Class
Hypertension
Valsartan dose equivalence
Useful for replacing Valsartan formulations affected by the 2018 recall
REFERENCE BOOK
Screening for Hypertension | CTFPHC
Summary
Clinician Summary
Recommendations (PDF)
link ⇲
Systematic Review
link ⇲
Tools/Resources
Clinician Algorithm (PDF)
link ⇲
Invasive Hemodynamics
AS: Aortic Valve Area (Gorlin)
Estimate aortic valve area
AS: Aortic Valve Area (Hakki)
Estimate aortic valve area
Cardiac Output - Fick
Calculate cardiac output, cardiac index, stroke volume and stroke volume index
MS: Mitral Valve Area (Gorlin)
MS: Mitral Valve Area (Hakki)
Pulmonary Resistance
Shunt Fraction (Invasive)
Systemic Vascular Resistance
Ischemic Stroke
GARFIELD-AF Risk Calculator
Compare the effects of different anticoagulant treatment decisions in atrial fibrillation
Miscellaneous
Duke Criteria for Endocarditis
Diagnose endocarditis
Metabolic Syndrome (IDF)
Jones Criteria for Diagnosis of Rheumatic Fever
Diagnose acute rheumatic fever
RPDAI (Relapsing Polychondritis Disease Activity Index)
Assess disease activity in relapsing polychondritis.
Mitral Regurgitation
MR: Quantification (PISA)
MR: Quantification (Volumetric)
Mitral Stenosis
MS: Wilkins' Echo Score
MS: Mitral Valve Area (Cont)
MS: Mitral Valve Area (Gorlin)
MS: Mitral Valve Area (PHT)
MS: Mitral Valve Area (PISA)
MS: Mitral Valve Area (Hakki)
PCI and Cardiac Surgery
British Columbia PCI risk score
Estimate 30-day mortality after percutaneous coronary intervention
BC Cardiac Surgical Intensive Care Score
Predict mortality after cardiac surgery based on preoperative and intraoperative variables assessed at admission to a cardiac surgery ICU
Dialysis Risk After Cardiac Surgery (Cleveland Clinic Score by Thakar)
Estimate risk of dialysis after cardiac surgery.
Dialysis Risk After Cardiac Surgery (Mehta)
Estimate the risk of dialysis after cardiac surgery (Mehta model)
PCI complication - Mayo
PCI mortality - Michigan
DAPT Score
Which patients should remain on dual anti-platelet therapy 1 year following coronary stent treatment?
NCDR AKI and Dialysis Risk after PCI
Estimate risk of AKI and dialysis after PCI
ECABG score
Predict emergency coronary artery bypass graft surgery after elective percutaneous coronary intervention
Pre-operative Assessment
Revised Cardiac Risk Index (Lee Criteria)
Rapid pre-op assessment using the Revised Cardiac Risk Index
Asymptomatic ICA (Internal Carotid Artery) Stenosis Surgical Risk Stratification
Gupta Perioperative Cardiac Risk
Determine peri-operative risk for a wide variety of surgeries
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Carotid Endarterectomy
Estimate risk of post-op myocardial infarction after carotid endarterectomy
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | EVAR
Estimate risk of post-op myocardial infarction after EVAR
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Infra-inguinal Bypass
Estimate risk of post-op myocardial infarction after infra-inguinal bypass
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Open AAA Repair
Estimate risk of post-op myocardial infarction after open AAA repair
Vascular Quality Initiative (VQI) Cardiac Risk Index (CRI) | Suprainguinal Bypass
Estimate risk of post-op myocardial infarction after suprainguinal bypass
Geriatric-Sensitive Perioperative Cardiac Risk Index | GSCRI
Estimate risk of perioperative myocardial infarction or cardiac arrest in patients over 65
ASA Physical Status
Classification system for assessing the fitness of patients before surgery
VISION perioperative risk using NT-proBNP
Predict risk of MI, vascular death, and all-cause death in patients having non-cardiac surgery
Risk Scores
ACC/AHA CV Risk Calculator (2013)
Estimate 10-year risk for atherosclerotic cardiovascular disease
Reynolds CAD Risk
Framingham Risk Score (2008)
Framingham Risk Score (ATP-III)
Determine lipid treatment using Framingham Risk Score
GARFIELD-AF Risk Calculator
Compare the effects of different anticoagulant treatment decisions in atrial fibrillation
Emergency Department Detection of Chest Pain Score (EDACS)
Identifies chest pain patients at low-risk for major adverse cardiac events
Troponin-only Manchester Acute Coronary Syndromes (TMACS) Decision Aid
Identify chest pain patients at low-risk for major adverse cardiac events
Shunts
Shunt Fraction (Echo)
Shunt Fraction (Invasive)
Syncope
Syncope - EGSYS Score
Which patients with syncope should be admitted?
San Francisco Syncope Rule
Identify those at low risk of adverse outcome after a syncopal episode
Canadian Syncope Risk Score (CSRS)
Estimate prognosis among patients presenting to emergency with syncope
FAINT Score in Syncope
Identify low-risk patients 60 years or older presenting with syncope
Treadmill Testing
Pretest Probablity of CAD
Duke Treadmill Score
Exercise Capacity (METs)
Rate Pressure Product
Pre-test probability of CAD (CAD consortium)
Determine pre-test probability of coronary artery disease in patients with chest pain.
Vascular Quality Initiative Tools
VQI Infrainguinal revascularization (open or PVI) for CLTI: 30 day and 2 year survival
The Vascular Quality Initiative Prediction Model for survival after infrainguinal revascularization
Critical Care
Cardiac ICU
Cardiac Output - Fick
Calculate cardiac output, cardiac index, stroke volume and stroke volume index
Killip Class
Estimate mortality in myocardial infarction
TIMI Risk Score (NSTEMI)
Guide therapeutic decisions in non-ST elevation MI.
Shunt Fraction (Invasive)
TIMI Risk Score (STEMI)
Systemic Vascular Resistance
GRACE
The GRACE ACS risk calculator estimates risk of death following acute coronary syndrome (ACS)
Mean Arterial Pressure (MAP)
Calculate MAP
ECABG score
Predict emergency coronary artery bypass graft surgery after elective percutaneous coronary intervention
REFERENCE BOOK
KDIGO Clinical Practice Guideline for Acute Kidney Injury
Sponsored
AKI Definition
Prevention and Treatment of AKI
Contrast-induced AKI
Dialysis Interventions for Treatment of AKI
Introduction and Methodology
Introduction
Introduction
Glomerular filtration rate and serum creatinine
Oliguria and anuria
Acute tubular necrosis (ATN)
ARF
RIFLE criteria
AKI: acute kidney injury/impairment
Validation studies using RIFLE
Limitations to current definitions for AKI
Rationale for a guideline on AKI
Summary
Methodology
Introduction
Group member selection and meeting process
Evidence selection, appraisal, and presentation
Outcome selection judgments, values, and preferences
Grading the quality of evidence and the strength of recommendations
SPONSORSHIP
DISCLAIMER
SUPPLEMENTARY MATERIAL
AKI Definition
Definition and classification of AKI
Introduction
Definition of AKI
Staging AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Risk assessment
Introduction
Recommendations and Rationale
Research Recommendations
Supplementary material
Evaluation and general management of patients with and at risk for AKI
Introduction
Recommendations and Rationale
Research recommendations
Supplementary material
Clinical applications
Introduction
Examples of application of AKI definitions
Estimating baseline SCr
Examples of application of AKI stages
Urine output vs. SCr
Timeframe for diagnosis and staging
Clinical judgment
Pseudo-AKI
Atypical AKI
Supplementary material
Diagnostic approach to alterations in kidney function and structure
Definitions of AKI, CKD and AKD
GFR and SCr
GFR/SCr algorithm
Oliguria as a measure of kidney function
Kidney damage
Small kidneys as a marker of kidney damage
Integrated approach to AKI, AKD, and CKD
Sponsorship
Disclaimer
Supplementary material
Prevention and Treatment of AKI
Hemodynamic monitoring and support for prevention and management of AKI
Introduction
Fluids: Recommendations and Rationale
Albumin vs. Saline
Hydroxyethylstarch vs. Saline
Vasopressors: Recommendations and Rationale
Protocolized Hemodynamic Management: Recommendations and Rationale
Protocolized hemodynamic management strategies in septic shock
Goal-directed therapy for hemodynamic support during the perioperative period in high-risk surgical patients
Research Recommendations
Supplementary material
General supportive management of patients with AKI, including management of complications
Overview
Glycemic control and nutritional support
Glycemic control in critical illness: Recommendations and Rationale
Nutritional aspects in the prevention and treatment of critically ill patients with AKI
Total Energy Intake: Recommendations and Rationale
Protein Intake: Recommendations and Rationale
Nutrition route: Recommendations and Rationale
Pediatrics Considerations
Research Recommendations
Supplementary material
The use of diuretics in AKI
Introduction
Recommendations and Rationale
Mannitol
Research Recommendations
Vasodilator therapy: dopamine, fenoldopam, and natriuretic peptides
Dopamine for the prevention or treatment of AKI: Recommendations and Rationale
Fenoldopam for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Natriuretic peptides for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Supplementary Material
Growth factor intervention
Recombinant Human (rh) IGF-1: Recommendations and Rationale
Erythropoietin
Research Recommendations
Supplementary Material
Adenosine receptor antagonists
Introduction
Recommendations and Rationale
Research Recommendations
Prevention of aminoglycoside- and amphotericin-related AKI
Aminoglycoside nephrotoxicity
Treatment of Infections: Recommendations and Rationale
Patients with Normal Kidney Function in Steady State: Recommendations and Rationale
When Treatment with Multiple Daily Dosing is Used for More than 24 Hours: Recommendations and Rationale
When Treatment with Single-Daily Dosing is Used for More than 48 Hours: Recommendations and Rationale
Topical or Local Applications of Aminoglycosides: Recommendations and Rationale
Research Recommendations
Amphotericin B nephrotoxicity: Recommendations and Rationale
Treatment of Systemic Mycoses or Parasitic Infections: Recommendations and Rationale
Research Recommendations
Other methods of prevention of AKI in the critically ill
On-pump vs. off-pump coronary artery bypass surgery: Recommendations and Rationale
Research Recommendations
N-ACETYLCYSTEINE (NAC): Recommendations and Rationale
NAC in critically ill patients: Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary Material
Contrast-induced AKI
Contrast-induced AKI: definition, epidemiology, and prognosis
Background
Recommendations and Rationale
Epidemiology of CI-AKI
Prognosis of CI-AKI
Research Recommendations
Supplementary Material
Assessment of the population at risk for CI-AKI
Recommendations and Rationale
Risk-factor questionnaire
Urinary protein screening
Other risk factors of CI-AKI
Risk models of CI-AKI
Patients at Increased Risk for CI-AKI: Recommendations and Rationale
Nephrotoxicity of Gd chelates
Nephrogenic systemic fibrosis (NSF)
Supplementary Material
Nonpharmacological prevention strategies of CI-AKI
Introduction
Dose/Volume of Contrast-Media Administration: Recommendations and Rationale
Route of administration of contrast media
Research Recommendations
Selection of a Contrast Agent: Recommendations and Rationale
High-osmolar vs. iso-osmolar or low-osmolar contrast media
Low-osmolar vs. iso-osmolar contrast media
i.a. Iodixanol vs. ioxaglate
i.v. Administration
Research Recommendations
Supplementary Material
Pharmacological prevention strategies of CI-AKI
Fluid Administration: Recommendations and Rationale
Use of oral fluids alone in patients at increased risk of CI-AKI: Recommendations and Rationale
Role of nac in the prevention of CI-AKI: Recommendations and Rationale
Theophylline: Recommendations and Rationale
Fenoldopam: Recommendations and Rationale
Statins in the prevention of CI-AKI
Supplementary Material
Effects of hemodialysis or hemofiltration
Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary material
Dialysis Interventions for Treatment of AKI
Timing of renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Criteria for stopping renal replacement therapy in AKI
Introduction
When to discontinue RRT: Recommendations and Rationale
Use of diuretics: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Anticoagulation
Introduction
How to decide to use anticoagulation: Recommendations and Rationale
Patients without an increased bleeding risk or impaired coagulation and not already receiving effective systemic anticoagulation: Recommendations and Rationale
Patients with increased bleeding risk who are not receiving anticoagulation: Recommendations and Rationale
In patients with heparin-induced thrombocytopenia: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Vascular access for renal replacement therapy in AKI
Introduction
Uncuffed nontunneled dialysis catheter vs a tunneled catheter: Recommendations and Rationale
When choosing a vein for insertion of a dialysis catheter in patients with AKI: Recommendations and Rationale
Using ultrasound guidance for dialysis catheter insertion: Recommendations and Rationale
Obtaining a chest radiograph promptly after placement and before first use of an internal jugular or subclavian dialysis catheter: Recommendations and Rationale
Topical antibiotics: Recommendations and Rationale
Antibiotic locks: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Dialyzer membranes for renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Research Recommendations
Modality of renal replacement therapy for patients with AKI
Introduction
Complementary therapies in AKI patients: Recommendations and Rationale
Hemodynamically unstable patients: Recommendations and Rationale
AKI patients with acute brain injury or other causes of increased intracranial pressure or generalized brain edema: Recommendations and Rationale
Protocols for decreasing hemodynamic instability with intermittent RRT
Peritoneal dialysis
Pediatric considerations
Research Recommendations
Supplementary material
Buffer solutions for renal replacement therapy in patients with AKI
Introduction
Buffer solution: Recommendations and Rationale
Dialysis fluids and replacement fluids in patients with AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Dose of renal replacement therapy in AKI
Introduction
Dosing: Recommendations and Rationale
Kt/V and Effluent Volume Rates: Recommendations and Rationale
Additional considerations
Research Recommendations
Sponsorship
Dislcaimer
Supplementary material
Organization and Acknowledgements
Notice
Work Group Membership
KDIGO Board Members
Reference Keys
Abbreviations and Acronyms
Abstract
Foreword
Biographic and Disclosure Information
Acknowledgments
References
General Medicine
Modified Early Warning Score (MEWS)
Identify patients who are at risk of clinical deterioration and who may require a higher level of care.
ICU AKI
APACHE II
Estimate mortality in the critically ill
Contrast Nephropathy Post-PCI
Estimate risk of AKI after percutaneous coronary intervention
Dialysis Risk After Cardiac Surgery (Cleveland Clinic Score by Thakar)
Estimate risk of dialysis after cardiac surgery.
Dialysis Risk After Cardiac Surgery (Mehta)
Estimate the risk of dialysis after cardiac surgery (Mehta model)
Fractional Excretion of Sodium
Differentiate pre-renal AKI from ATN.
Fractional Excretion of Urea
Identify a pre-renal state in patients using diuretics
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
Pediatric Renal Angina Index
Predict acute kidney injury in critically ill children
STARRT-AKI Enrollment Criteria
Determine if patients meet criteria for the STARRT-AKI study.
Kinetic eGFR (KeGFR)
Estimate GFR when creatinine is changing acutely (either rising or falling)
PIM2
Paediatric Index of Mortality, revised version
Serious Renal Dysfunction Post-PCI
Assess risk of dialysis or severe increase in creatinine after PCI
CRRT Dosing Calculator
Calculate desired dose of dialysate in CRRT
KDIGO AKI Staging
Classification in acute kidney injury (AKI)
REFERENCE BOOK
KDIGO Clinical Practice Guideline for Acute Kidney Injury
Sponsored
AKI Definition
Prevention and Treatment of AKI
Contrast-induced AKI
Dialysis Interventions for Treatment of AKI
Introduction and Methodology
Introduction
Introduction
Glomerular filtration rate and serum creatinine
Oliguria and anuria
Acute tubular necrosis (ATN)
ARF
RIFLE criteria
AKI: acute kidney injury/impairment
Validation studies using RIFLE
Limitations to current definitions for AKI
Rationale for a guideline on AKI
Summary
Methodology
Introduction
Group member selection and meeting process
Evidence selection, appraisal, and presentation
Outcome selection judgments, values, and preferences
Grading the quality of evidence and the strength of recommendations
SPONSORSHIP
DISCLAIMER
SUPPLEMENTARY MATERIAL
AKI Definition
Definition and classification of AKI
Introduction
Definition of AKI
Staging AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Risk assessment
Introduction
Recommendations and Rationale
Research Recommendations
Supplementary material
Evaluation and general management of patients with and at risk for AKI
Introduction
Recommendations and Rationale
Research recommendations
Supplementary material
Clinical applications
Introduction
Examples of application of AKI definitions
Estimating baseline SCr
Examples of application of AKI stages
Urine output vs. SCr
Timeframe for diagnosis and staging
Clinical judgment
Pseudo-AKI
Atypical AKI
Supplementary material
Diagnostic approach to alterations in kidney function and structure
Definitions of AKI, CKD and AKD
GFR and SCr
GFR/SCr algorithm
Oliguria as a measure of kidney function
Kidney damage
Small kidneys as a marker of kidney damage
Integrated approach to AKI, AKD, and CKD
Sponsorship
Disclaimer
Supplementary material
Prevention and Treatment of AKI
Hemodynamic monitoring and support for prevention and management of AKI
Introduction
Fluids: Recommendations and Rationale
Albumin vs. Saline
Hydroxyethylstarch vs. Saline
Vasopressors: Recommendations and Rationale
Protocolized Hemodynamic Management: Recommendations and Rationale
Protocolized hemodynamic management strategies in septic shock
Goal-directed therapy for hemodynamic support during the perioperative period in high-risk surgical patients
Research Recommendations
Supplementary material
General supportive management of patients with AKI, including management of complications
Overview
Glycemic control and nutritional support
Glycemic control in critical illness: Recommendations and Rationale
Nutritional aspects in the prevention and treatment of critically ill patients with AKI
Total Energy Intake: Recommendations and Rationale
Protein Intake: Recommendations and Rationale
Nutrition route: Recommendations and Rationale
Pediatrics Considerations
Research Recommendations
Supplementary material
The use of diuretics in AKI
Introduction
Recommendations and Rationale
Mannitol
Research Recommendations
Vasodilator therapy: dopamine, fenoldopam, and natriuretic peptides
Dopamine for the prevention or treatment of AKI: Recommendations and Rationale
Fenoldopam for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Natriuretic peptides for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Supplementary Material
Growth factor intervention
Recombinant Human (rh) IGF-1: Recommendations and Rationale
Erythropoietin
Research Recommendations
Supplementary Material
Adenosine receptor antagonists
Introduction
Recommendations and Rationale
Research Recommendations
Prevention of aminoglycoside- and amphotericin-related AKI
Aminoglycoside nephrotoxicity
Treatment of Infections: Recommendations and Rationale
Patients with Normal Kidney Function in Steady State: Recommendations and Rationale
When Treatment with Multiple Daily Dosing is Used for More than 24 Hours: Recommendations and Rationale
When Treatment with Single-Daily Dosing is Used for More than 48 Hours: Recommendations and Rationale
Topical or Local Applications of Aminoglycosides: Recommendations and Rationale
Research Recommendations
Amphotericin B nephrotoxicity: Recommendations and Rationale
Treatment of Systemic Mycoses or Parasitic Infections: Recommendations and Rationale
Research Recommendations
Other methods of prevention of AKI in the critically ill
On-pump vs. off-pump coronary artery bypass surgery: Recommendations and Rationale
Research Recommendations
N-ACETYLCYSTEINE (NAC): Recommendations and Rationale
NAC in critically ill patients: Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary Material
Contrast-induced AKI
Contrast-induced AKI: definition, epidemiology, and prognosis
Background
Recommendations and Rationale
Epidemiology of CI-AKI
Prognosis of CI-AKI
Research Recommendations
Supplementary Material
Assessment of the population at risk for CI-AKI
Recommendations and Rationale
Risk-factor questionnaire
Urinary protein screening
Other risk factors of CI-AKI
Risk models of CI-AKI
Patients at Increased Risk for CI-AKI: Recommendations and Rationale
Nephrotoxicity of Gd chelates
Nephrogenic systemic fibrosis (NSF)
Supplementary Material
Nonpharmacological prevention strategies of CI-AKI
Introduction
Dose/Volume of Contrast-Media Administration: Recommendations and Rationale
Route of administration of contrast media
Research Recommendations
Selection of a Contrast Agent: Recommendations and Rationale
High-osmolar vs. iso-osmolar or low-osmolar contrast media
Low-osmolar vs. iso-osmolar contrast media
i.a. Iodixanol vs. ioxaglate
i.v. Administration
Research Recommendations
Supplementary Material
Pharmacological prevention strategies of CI-AKI
Fluid Administration: Recommendations and Rationale
Use of oral fluids alone in patients at increased risk of CI-AKI: Recommendations and Rationale
Role of nac in the prevention of CI-AKI: Recommendations and Rationale
Theophylline: Recommendations and Rationale
Fenoldopam: Recommendations and Rationale
Statins in the prevention of CI-AKI
Supplementary Material
Effects of hemodialysis or hemofiltration
Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary material
Dialysis Interventions for Treatment of AKI
Timing of renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Criteria for stopping renal replacement therapy in AKI
Introduction
When to discontinue RRT: Recommendations and Rationale
Use of diuretics: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Anticoagulation
Introduction
How to decide to use anticoagulation: Recommendations and Rationale
Patients without an increased bleeding risk or impaired coagulation and not already receiving effective systemic anticoagulation: Recommendations and Rationale
Patients with increased bleeding risk who are not receiving anticoagulation: Recommendations and Rationale
In patients with heparin-induced thrombocytopenia: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Vascular access for renal replacement therapy in AKI
Introduction
Uncuffed nontunneled dialysis catheter vs a tunneled catheter: Recommendations and Rationale
When choosing a vein for insertion of a dialysis catheter in patients with AKI: Recommendations and Rationale
Using ultrasound guidance for dialysis catheter insertion: Recommendations and Rationale
Obtaining a chest radiograph promptly after placement and before first use of an internal jugular or subclavian dialysis catheter: Recommendations and Rationale
Topical antibiotics: Recommendations and Rationale
Antibiotic locks: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Dialyzer membranes for renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Research Recommendations
Modality of renal replacement therapy for patients with AKI
Introduction
Complementary therapies in AKI patients: Recommendations and Rationale
Hemodynamically unstable patients: Recommendations and Rationale
AKI patients with acute brain injury or other causes of increased intracranial pressure or generalized brain edema: Recommendations and Rationale
Protocols for decreasing hemodynamic instability with intermittent RRT
Peritoneal dialysis
Pediatric considerations
Research Recommendations
Supplementary material
Buffer solutions for renal replacement therapy in patients with AKI
Introduction
Buffer solution: Recommendations and Rationale
Dialysis fluids and replacement fluids in patients with AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Dose of renal replacement therapy in AKI
Introduction
Dosing: Recommendations and Rationale
Kt/V and Effluent Volume Rates: Recommendations and Rationale
Additional considerations
Research Recommendations
Sponsorship
Dislcaimer
Supplementary material
Organization and Acknowledgements
Notice
Work Group Membership
KDIGO Board Members
Reference Keys
Abbreviations and Acronyms
Abstract
Foreword
Biographic and Disclosure Information
Acknowledgments
References
Illness Severity
APACHE II
Estimate mortality in the critically ill
Ranson's Criteria
Estimate mortality in patients with pancreatitis.
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
BISAP Score
Estimate disease severity in acute pancreatitis.
Modified Glasgow Imrie Severity Criteria for Acute Pancreatitis
Predict outcome in acute pancreatitis
UKELD Score
The United Kingdom Model for End-Stage Liver Disease (UKELD) predicts prognosis in chronic liver disease and can be used to prioritize for liver transplantation
SWAP Score for Out of Hospital Cardiac Arrest
Predicts which patients with OHCA will have poor neurologic recovery
Medical ICU
Child Pugh Score
Determine severity and estimate mortality in cirrhosis
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
Parkland Formula
Manage IV fluids required in burns
Ranson's Criteria
Estimate mortality in patients with pancreatitis.
Serious Illness Conversation Guide
Steps to elicit important information from your patients about their goals and values
Modified Glasgow Imrie Severity Criteria for Acute Pancreatitis
Predict outcome in acute pancreatitis
UKELD Score
The United Kingdom Model for End-Stage Liver Disease (UKELD) predicts prognosis in chronic liver disease and can be used to prioritize for liver transplantation
Modified Early Warning Score (MEWS)
Identify patients who are at risk of clinical deterioration and who may require a higher level of care.
Mean Arterial Pressure (MAP)
Calculate MAP
Predicting Ionized Hypocalcemia in Critical Care
In critical care patients, estimate the single most likely ionised calcium value--with its surrounding 95% range of likely values--as well as the chance the true value is under 1.10 mM. The reference range for arterial iCa is 1.15-1.29 mM.
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Rule of Nines
Estimate surface area of burns
Neurologic ICU
Cerebral Perfusion Pressure
Calculate net pressure gradient causing cerebral blood flow to the brain
FOUR Score
Glasgow Coma Scale (GCS)
Document level of consciousness.
CIWA-Ar
Optimize benzodiazepine treatment of patients alcohol withdrawal
CAM-ICU
Diagnose delirium in the intensive care unit.
The Richmond Agitation Sedation Score (RASS)
Assess level of consciousness in the intensive care unit.
Respiratory ICU
A-a Gradient
Used to determine cause of hypoxemia
Pulmonary Embolism Severity Index (PESI)
Predict outcome in patients with pulmonary embolism
PE Clinical Probability
Determine pretest probability of PE to guide workup
Pneumonia risk (CURB-65)
Estimate prognosis and determine disposition in community-acquired pneumonia. Not yet validated in COVID-19
Pulmonary Resistance
Pneumonia Severity Index (PORT Score)
Determine need for admission in pneumonia. Not yet validated in COVID-19.
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
ROX Index to Predict Risk of Intubation
Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19
COVID-19 Ventilation Protocol
Adapted from an algorithm developed by The Toronto Centre of Excellence in Mechanical Ventilation (CoEMV)
ProVent 14 Score for prolonged mechanical ventilation
Determine risk of 1-year mortality after prolonged mechanical ventilation
Sepsis
SIRS Criteria (Systemic Inflammatory Response Syndrome)
Identify systemic inflammatory response to an infectious or non-infectious insult
qSOFA Score in Septic Patients
Predict patients at high-mortality risk from sepsis (not diagnose sepsis)
Sepsis Induced Coagulopathy (SIC) Score
Estimate risk of sepsis-induced coagulopathy
Trauma
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
ABC Score for Massive Transfusion
Predict necessity for massive transfusion in trauma patients
Emergency
Airway
Modified Mallampati Classification
Oropharyngeal assessment used for predicting difficulty in laryngoscopy and endotracheal intubation
Burns
Parkland Formula
Manage IV fluids required in burns
Rule of Nines
Estimate surface area of burns
Chest Pain & Cardiac
Infarct Size - Anterior
Estimate infarct size in anterior MI
Infarct Size - Inferior
Estimate infarct size in inferior MI
HEART Score | Chest pain in the ER
Risk stratify patients with chest pain in the ER
Killip Class
Estimate mortality in myocardial infarction
TIMI Risk Score (NSTEMI)
Guide therapeutic decisions in non-ST elevation MI.
TIMI Risk Score (STEMI)
GRACE
The GRACE ACS risk calculator estimates risk of death following acute coronary syndrome (ACS)
Pre-test probability of CAD (CAD consortium)
Determine pre-test probability of coronary artery disease in patients with chest pain.
ADviSED - Aortic Dissection Detection Risk Score Plus D-Dimer for Aortic Syndromes
Rule out aortic dissection and other aortic syndromes
Smith-Modified Sgarbossa’s Criteria for MI in Left Bundle Branch Block
Diagnose acute MI in patients with known LBBB
Sgarbossa’s Criteria for MI in Left Bundle Branch Block
Allows for the diagnosis of acute MI in patients with known LBBB
Emergency Heart Failure Mortality Risk Grade (EHMRG)
Risk stratify patients with acutely decompensated heart failure
Brugada Criteria for Ventricular Tachycardia
ECG criteria to help differentiate ventricular tachycardia from supraventricular tachycardia.
FAINT Score in Syncope
Identify low-risk patients 60 years or older presenting with syncope
Emergency Department Detection of Chest Pain Score (EDACS)
Identifies chest pain patients at low-risk for major adverse cardiac events
Troponin-only Manchester Acute Coronary Syndromes (TMACS) Decision Aid
Identify chest pain patients at low-risk for major adverse cardiac events
SWAP Score for Out of Hospital Cardiac Arrest
Predicts which patients with OHCA will have poor neurologic recovery
sPESI | simplified Pulmonary Embolism Severity Index
Estimate risk of 30-day mortality in patients with acute PE
General Medicine
ECG: Heart Rate
A-a Gradient
Used to determine cause of hypoxemia
Anion Gap
Calculate anion gap for workup of acid-base disorders
CHADS2 Score for Atrial Fibrillation
Assess risk of stroke in atrial fibrillation
CHA2DS2-VASc Score for AF
Replacement for CHADS2 for stroke prediction in atrial fibrillation
Child Pugh Score
Determine severity and estimate mortality in cirrhosis
ECG: Corrected QT
Calculate the corrected QT interval
ECG: Cycle Length
Fractional Excretion of Sodium
Differentiate pre-renal AKI from ATN.
MDRD eGFR
Calculate eGFR using the MDRD formula
Prognosis after TIPSS using MELD Score
Osmolal Gap
Detect unmeasured osmoles, such as toxic alcohols
Peak Expiratory Flow Prediction
Pneumonia risk (CURB-65)
Estimate prognosis and determine disposition in community-acquired pneumonia. Not yet validated in COVID-19
Ranson's Criteria
Estimate mortality in patients with pancreatitis.
Water Deficit in Hypernatremia
Determine water replacement in hypernatremia
Canadian Syncope Risk Score (CSRS)
Estimate prognosis among patients presenting to emergency with syncope
ROSIER scale
Determine which patients are likely to have true stroke vs stroke mimics
Modified Early Warning Score (MEWS)
Identify patients who are at risk of clinical deterioration and who may require a higher level of care.
Mean Arterial Pressure (MAP)
Calculate MAP
Centor Score (modified) for GAS Pharyngitis
Estimate likelihood of GAS pharyngitis
Maintenance Fluid Calculations
Determine maintenance IV fluid rates
Ottawa chronic obstructive pulmonary disease risk scale (OCRS)
Guide admission vs discharge in COPD exacerbation
Light's Criteria
Determine whether a pleural effusion is exudative or transudative
McMahon Rhabdomyolysis Risk Score
Predict the risk of severe acute kidney injury or mortality in patients with rhabdomyolysis
Kocher Criteria for Septic Arthritis
Determine risk of septic arthritis in a child with an inflamed hip
Shock Index
A more sensitive quotient for circulatory shock than vital signs alone
Acute Gout Diagnosis Rule
Clinical decision tool to assist in the diagnosis of acute gout
Sodium Correction Rate for Hyponatremia
Rate of fluid administration in correction of hyponatremia
IV Drip Rate Calculator
Assistance in calculating accurate rates of medication administration
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
sPESI | simplified Pulmonary Embolism Severity Index
Estimate risk of 30-day mortality in patients with acute PE
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
Canadian TIA Score
Estimate 7-day Risk of Stroke or Carotid Revascularization
CCS Angina Class
Injuries & Trauma
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
Canadian C-Spine Rule
Determine whether cervical spine imaging can be safely avoided
NEXUS C-Spine Criteria
Determine whether cervical spine imaging can be safely avoided
Ottawa Ankle Rules
Does this ankle injury require an x-ray?
Ottawa Knee Rules
Does this knee injury require an x-ray?
Ottawa SAH Rule
Use the Ottawa SAH Rule to rule out subarachnoid hemorrhage
Injury Severity Score
Describe severity of traumatic injury
ABC Score for Massive Transfusion
Predict necessity for massive transfusion in trauma patients
Pittsburgh Knee Rule
Assist with detection of knee fractures and decision to x-ray
McMahon Rhabdomyolysis Risk Score
Predict the risk of severe acute kidney injury or mortality in patients with rhabdomyolysis
Testicular Workup for Ischemia and Suspected Torsion (TWIST) score
Estimate probability of torsion in acute testicular pain
Pediatrics ER
APGAR
Rapid newborn clinical assessment
Pediatric Endotracheal Tube Size
Pediatric Glasgow Coma Scale
Pediatric Strep Score
PELD Score - Age Younger Than 12 years
PELD (Pediatric End-Stage Liver Disease) is used for liver allocation in the OPTN match system
Westley Croup Score
Assess croup severity
Philadelphia Criteria in Febrile Infants
Identify febrile infants aged 29 – 56 days old who are lower risk for serious bacterial infection
Boston Criteria for Febrile Infants
Identify febrile infants aged 28 – 89 days old who are lower risk for serious bacterial infection
Rochester Criteria for Febrile Infants
Identify febrile infants aged ≤ 60 days old who are low-risk for serious bacterial infection
PECARN Rule for Pediatric Head Injury < 2 years old
Assess the need for neuroimaging in pediatric head trauma
PECARN Rule for Pediatric Head Injury ≥ 2 years old
Assess the need for neuroimaging in pediatric head trauma
PRAM Score for Pediatric Asthma Exacerbation Severity
Assess asthma severity in pediatric patients
Attia Criteria for Evaluation of Pharyngitis
Estimate likelihood of Streptococcal pharyngitis as the etiology for sore throat
Testicular Workup for Ischemia and Suspected Torsion (TWIST) score
Estimate probability of torsion in acute testicular pain
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Bacterial Meningitis Score for Children
Risk stratification tool for children with possible bacterial meningitis
Alberta Croup Severity
Psychiatry
Modified SAD PERSONS Scale
Assess depression with the modified SAD PERSONS Scale
CIWA-Ar
Optimize benzodiazepine treatment of patients alcohol withdrawal
COWS Score for Opiate Withdrawal
Abnormal Involuntary Movement Scale (AIMS)
12-item scale to assess severity of dyskinesias
Bush-Francis Catatonia Rating Scale (BFCRS)
23 questions to assess the severity of catatonia.
Columbia-Suicide Severity Rating Scale (C-SSRS)
5-question suicide risk assessment.
Sepsis
SIRS Criteria (Systemic Inflammatory Response Syndrome)
Identify systemic inflammatory response to an infectious or non-infectious insult
qSOFA Score in Septic Patients
Predict patients at high-mortality risk from sepsis (not diagnose sepsis)
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Sepsis Induced Coagulopathy (SIC) Score
Estimate risk of sepsis-induced coagulopathy
Bacterial Meningitis Score for Children
Risk stratification tool for children with possible bacterial meningitis
Surgery
Alvarado Score for Acute Appendicitis
Diagnose appendicitis
VSGNE Ruptured Abdominal Aortic Aneurysm (RAAA) Risk Score
Estimate mortality after open repair of ruptured AAA
Modified Glasgow Imrie Severity Criteria for Acute Pancreatitis
Predict outcome in acute pancreatitis
Thrombosis
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
Pulmonary Embolism Severity Index (PESI)
Predict outcome in patients with pulmonary embolism
PE Clinical Probability
Determine pretest probability of PE to guide workup
PERC Rule for Pulmonary Embolism
Use the PERC rule to rule out PE if no criteria are present and pre-test probability is <15%.
Hestia Criteria for Outpatient Management of Pulmonary Embolism
Identify patients with acute PE who may be appropriate for outpatient management
Endocrinology
Diabetes
FINDRISC Diabetes Risk Calculator
Estimate risk of developing diabetes and frequency of screening required.
Reducing Vascular Risk in Patients Living with Diabetes
Determine which patients with diabetes require vascular protective therapy
Physical Activity Decision Tool for Patients Living with Diabetes
Assess your patient's physical ability and level of motivation to start and/or progress through a physical activity program.
Individualizing Your Patient's A1c Target
Determine a patient-specific A1C target recommendation
Self-Monitoring Blood Glucose (SMBG)
Determine frequency of blood glucose monitoring
Screening For And Diagnosing Diabetes - A1c and Fasting Plasma Glucose
Determine risk of developing diabetes and frequency of screening required
Pharmacotherapy for Type 2 Diabetes
Determine which type 2 diabetes medications are recommended based on patient characteristics.
Screening For And Diagnosing Diabetes - 75g Oral Glucose Tolerance Test (OGTT)
Determine risk of developing diabetes and frequency of screening required
Screening For And Diagnosing Gestational Diabetes Mellitus (GDM)
Assess for gestational diabetes mellitus
Diabetes Risk Score (Type 2)
Calculate risk of developing T2DM
Optimizing Care in Diabetic Kidney Disease
Ensure application of evidence-based care in diabetic kidney disease (DKD)
Sponsored
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
REFERENCE BOOK
Screening for Type 2 Diabetes | CTFPHC
Summary
Clinician Summary
Recommendations (CMAJ)
link ⇲
Systematic Review
link ⇲
Tools/Resources
FINDRISC Diabetes Risk Calculator
Clinician FAQ
link ⇲
Patient FAQ
link ⇲
Electrolytes
Calcium Correction for Hypoalbuminemia
Adjust serum calcium in the setting of low albumin
Predicting Ionized Hypocalcemia in Critical Care
In critical care patients, estimate the single most likely ionised calcium value--with its surrounding 95% range of likely values--as well as the chance the true value is under 1.10 mM. The reference range for arterial iCa is 1.15-1.29 mM.
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
Lipids
Lipid Lowering Guidelines using Framingham (2008)
Lipid Lowering Guidelines using Framingham (ATP-III)
Familial Hypercholesterolemia
Diagnose familial hypercholesterolemia
Obesity
REFERENCE BOOK
Obesity in Adults | CTFPHC
Summary
Clinician Summary
Clinician FAQ
Clinician Algorithm - Calculator
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Obesity in Children | CTFPHC
Summary
Clinician Summary
Clinician Recommendation Table
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
Osteoporosis
Dubbo Osteoporotic Fracture Risk
Assess risk of osteoporotic fracture
Osteoporosis Self-Assessment Tool for Men
Risk stratify men for likelihood of osteoporosis
Osteoporosis Self-Assessment Tool for Women
Risk stratify women for likelihood of osteoporosis
Thyroid disease & cancer
Differentiated Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Anaplastic Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Medullary Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Gastroenterology
Diarrhea
Diagnosis of Clostridium Difficile Infection
Based on IDSA guidelines
Treatment of First Episode of Clostridium Difficile
Clinical management algorithm for adults, based on IDSA guidelines
Treatment of Recurrent Episode of Clostridium Difficile
Clinical management algorithm for adults, based on IDSA guidelines
GI Bleed
Blatchford Score
Assess if intervention is required for acute upper GI bleeding.
Forrest Classification
Estimate risk of re-bleeding post-endoscopy for upper GI bleeding.
Rockall Score
Estimate risk of mortality after endoscopy for GI bleed.
Gastric Cancer TNM Staging
TNM Staging | AJCC 2017
Gastrointestinal cancer
Colorectal Cancer
TNM Staging | AJCC 2017
Gastric Cancer TNM Staging
TNM Staging | AJCC 2017
Hepatocellular Carcinoma TNM Staging
TNM Staging | AJCC 2017
Esophagus and Esophagogastric Junction Cancers (Squamous Cell Carcinoma)
TNM Staging | AJCC 2017
Esophagus and Esophagogastric Junction Cancers (Adenocarcinoma)
TNM Staging | AJCC 2017
Hepatology
Autoimmune Hepatitis Diagnosis
Clarify the diagnose of autoimmune hepatitis
Child Pugh Score
Determine severity and estimate mortality in cirrhosis
Discriminant Function (Alcoholic Hepatitis)
Emory Model (TIPSS)
Prognosis after TIPSS using MELD Score
Prognosis in Alcoholic Hepatitis
Estimates prognosis in alcoholic hepatitis using the MELD score
PELD Score - Age Younger Than 12 years
PELD (Pediatric End-Stage Liver Disease) is used for liver allocation in the OPTN match system
Alcohol Addiction Risk of Relapse
Alcohol Relapse Risk after Liver Transplant
Serum Ascites to Albumin Gradient (SAAG)
Determine if ascites due to portal hypertension.
FIB-4 for Noninvasive Diagnosis of Hepatic Fibrosis
Non-invasively identify hepatic fibrosis
APRI (AST to Platelet Ratio Index)
Assess likelihood of fibrosis or cirrhosis non-invasively using AST and platelet count.
NAFLD Fibrosis Score
Reduce the need for liver biopsy by identifying patients with non-alcoholic fatty liver disease likely or unlikely to have advanced fibrosis
MELD Score - Age above 12 years
Scoring system used to rank prioritize candidates for liver transplantation, including MELD-Na used in the OPTN match system
UKELD Score
The United Kingdom Model for End-Stage Liver Disease (UKELD) predicts prognosis in chronic liver disease and can be used to prioritize for liver transplantation
Lille Model for Alcoholic Hepatitis
Estimate mortality in patients with severe alcoholic hepatitis not responding to corticosteroid therapy
BE3A Score
When to treat HCV in decompensated cirrhosis
Hepatocellular Carcinoma TNM Staging
TNM Staging | AJCC 2017
Inflammatory Bowel Disease
Crohn's Disease Activity Index (CDAI)
Assess disease activity in Crohn's disease
Mayo Score for Ulcerative Colitis Activity
Assess disease activity in ulcerative colitis
Urine Anion Gap or Urine Net Charge
Use urine electrolytes to differentiate renal tubular acidosis from diarrhea-induced non-anion gap metabolic acidosis
PCDAI
Pediatric Crohn's Disease Activity Index
Pancreatitis
APACHE II
Estimate mortality in the critically ill
CT Severity Index (Pancreatitis)
Predict complication and mortality rate in pancreatitis, based on CT findings (Balthazar score)
Ranson's Criteria
Estimate mortality in patients with pancreatitis.
BISAP Score
Estimate disease severity in acute pancreatitis.
Modified Marshall Score
A definition of organ failure in acute pancreatitis
Modified Glasgow Imrie Severity Criteria for Acute Pancreatitis
Predict outcome in acute pancreatitis
Geriatrics
Cardiac & Cerebrovascular
ABCD² Score
Guide admission in TIA based on ABCD² Score
ACC/AHA CV Risk Calculator (2013)
Estimate 10-year risk for atherosclerotic cardiovascular disease
CHADS2 Score for Atrial Fibrillation
Assess risk of stroke in atrial fibrillation
CHA2DS2-VASc Score for AF
Replacement for CHADS2 for stroke prediction in atrial fibrillation
Syncope - EGSYS Score
Which patients with syncope should be admitted?
Bleeding Risk in Atrial Fibrillation: HAS-BLED Score
Understand the risk of bleeding from anticoagulation in atrial fibrillation
Warfarin Bleeding Risk - Elderly
Estimate 90 day risk of bleeding in patients on warfarin who are >65 years
Bleeding Risk in Atrial Fibrillation: ATRIA
Estimate bleeding risk for patients on warfarin.
San Francisco Syncope Rule
Identify those at low risk of adverse outcome after a syncopal episode
Canadian Syncope Risk Score (CSRS)
Estimate prognosis among patients presenting to emergency with syncope
Geriatric-Sensitive Perioperative Cardiac Risk Index | GSCRI
Estimate risk of perioperative myocardial infarction or cardiac arrest in patients over 65
Seizure vs Syncope
Determine which patients are likely to have seizure versus syncope as the cause of loss of consciousness
Depression
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
16 question geriatric cognitive screener
Frailty
Dubbo Osteoporotic Fracture Risk
Assess risk of osteoporotic fracture
Edmonton Frail Scale
Simple tool to assess frailty in older patients
Osteoporosis Self-Assessment Tool for Men
Risk stratify men for likelihood of osteoporosis
Osteoporosis Self-Assessment Tool for Women
Risk stratify women for likelihood of osteoporosis
General Medicine
MGUS Prognosis
Determine risk of malignant progression to myleoma or lymphoproliferative disorder.
Pneumonia risk (CURB-65)
Estimate prognosis and determine disposition in community-acquired pneumonia. Not yet validated in COVID-19
Water Deficit in Hypernatremia
Determine water replacement in hypernatremia
Pneumonia Severity Index (PORT Score)
Determine need for admission in pneumonia. Not yet validated in COVID-19.
Patient Health Questionnaire-9 (PHQ-9)
Screening tool to assist in identifying major depressive disorder
Polymyalgia Rheumatica (2012 EULAR/ACR Provisional Criteria)
Review EULAR/ACR criteria for polymyalgia rheumatica
International Prostate Symptom Score (IPSS)
Assess severity of symptoms in benign prostatic hypertrophy
Geriatric Psychiatry
Hamilton Depression Rating Scale (HAM-D or HDRS)
Determine severity of depression
Geriatric Depression Scale
A questionnaire to screen for depression in geriatric populations
GAD-7 Anxiety Scale
Screen for generalized anxiety disorder
Short Michigan Alcoholism Screening Test-geriatric version The SMAST-G
Assess for problem alcohol drinking in the elderly
Kidney Disease
MGUS Prognosis
Determine risk of malignant progression to myleoma or lymphoproliferative disorder.
eGFR using CKD-EPI
Calculate eGFR using the CKD-EPI formula
3-Month Mortality in Incident Elderly ESRD Patients
Estimate the risk of early death (at 3 months) in elderly patients starting dialysis.
Predicting 3 Year Survival for Incident Elderly ESRD Patients
Determine appropriateness for transplant referral in elderly patients starting dialysis
Neurocognitive Disorder
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
16 question geriatric cognitive screener
Diagnosis of Dementia with Lewy Bodies (DLB)
Diagnose patients with dementia with Lewy Bodies based on the 2017 criteria
Diagnosis of Multiple System Atrophy (MSA)
Diagnose Multiple Systems Atrophy based on the 2008 criteria
Anticholinergic Burden Assessment Tool
A tool for finding the ACB Score of commonly prescribed medicines, and for calculating the Anticholinergic Burden for your patient.
Sponsored by Astellas Pharma
REFERENCE BOOK
Screening for Cognitive Impairment | CTFPHC
Summary
Clinician Summary
Clinician FAQ
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
Hematology
Benign Hematology
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
Pulmonary Embolism Severity Index (PESI)
Predict outcome in patients with pulmonary embolism
HIT 4T's score
Diagnose heparin-induced thrombocytopenia.
PE Clinical Probability
Determine pretest probability of PE to guide workup
Recognize Thrombotic Microangiopathy
Sponsored Content
Identify Type of Thrombotic Microangiopathy
Sponsored Content
PERC Rule for Pulmonary Embolism
Use the PERC rule to rule out PE if no criteria are present and pre-test probability is <15%.
Expected spleen size
Provides upper limit of normal for spleen length and volume by ultrasound relative to body height and gender.
Padua Prediction Score for Risk of VTE
Estimate risk of venous thromboembolism in hospitalized patients
Khorana risk score
Estimate risk of chemotherapy-associated thrombosis
PORT score for PeriOperative Risk of blood Transfusion in cardiac surgery by ACTA
Predict risk of blood transfusion after elective cardiac surgery using the ACTA-PORT score
Absolute Neutrophil Count (ANC)
Determine ANC to assess risk of opportunistic infection
Estimated Blood Volume
Blood volume estimate based on patient weight and demographics
DIC Score
Assess likelihood of disseminated intravascular coagulation (DIC)
H Score
Diagnoses reactive hemophagocytic syndrome (HLH or MAS)
Plasmic Score for TTP
Predict ADAMTS13 deficiency in suspected thrombotic thrombocytopenic purpura (TTP) with high discrimination.
sPESI | simplified Pulmonary Embolism Severity Index
Estimate risk of 30-day mortality in patients with acute PE
Hestia Criteria for Outpatient Management of Pulmonary Embolism
Identify patients with acute PE who may be appropriate for outpatient management
Sepsis Induced Coagulopathy (SIC) Score
Estimate risk of sepsis-induced coagulopathy
Body Surface Area
BMI and BSA (Mosteller)
Calculate BMI and Body Surface Area using Mosteller formula
BMI and BSA (Du Bois)
Determine body mass index and body surface area using Du Bois method
Body Surface Area Based Dosing
Medication dose adjustment based on body surface area (BSA)
Malignant Hematology
CMML Prognostic Scoring Systems (from Spain and Dusseldorf)
Assess risk of progression to AML and early mortality in CMML
Diffuse Large B-Cell Lymphoma Prognosis (R-IPI)
Determine prognosis in diffuse large B-cell lymphoma
Follicular Lymphoma prognosis
Determine prognosis in follicular lymphoma (FLIPI)
Acute GVHD Grading
Determine severity in acute graft versus host disease.
Hodgkin's Disease | Prognosis
Estimate prognosis in Hodgkin's disease.
Hematopoietic cell transplantation - specific comorbidity index (HCT-CI)
MDS Revised - International Prognostic Scoring System (IPSS-R)
Assess mortality and progression to acute myeloid leukemia in myelodysplastic syndrome
Hodgkin's Marrow Involvement
Estimate likelihood of bone marrow involvement in Hodgkin's lymphoma.
MDS International Prognostic Scoring System (IPSS)
Determine prognosis in myelodysplastic sydnrome
Multiple Myeloma Prognosis (ISS)
MASCC Febrile Neutropenia Risk
Assess risk in febrile neutropenia and appropriateness for outpatient management
MDS Anemia - EPO/GCSF Response
Identify those with MDS likely to respond to stem-cell factors.
MDS WHO Classification-based Prognostic Scoring System (WPSS)
Estimate survival and risk of transformation to AML in myelodysplastic syndrome.
MGUS Prognosis
Determine risk of malignant progression to myleoma or lymphoproliferative disorder.
MIPI - Mantle Cell Lymphoma Prognosis
Estimate prognosis in mantle cell lymphoma.
DIPSS Prognosis in Myelofibrosis
Estimate prognosis in myelofibrosis.
Smoldering Multiple Myeloma Prognosis
Determine risk of progression to symptomatic multiple myeloma.
Diffuse Large B-cell Lymphoma Prognosis (IPI24)
Determine prognosis in diffuse large B-cell lymphoma.
Diffuse Large B-cell Lymphoma Prognosis (NCCN-IPI)
Estimate prognosis in diffuse large B-cell lymphoma
DIPSS Plus Score for Prognosis in Myelofibrosis
Estimate prognosis in myelofibrosis.
Multiple Myeloma Prognosis (R-ISS)
Revised international staging system for myeloma
CLL-IPI
The International Prognostic Index for patients with chronic lymphocytic leukemia
Expected spleen size
Provides upper limit of normal for spleen length and volume by ultrasound relative to body height and gender.
MDS Revised - International Prognostic Scoring System (IPSS-R) Non-Age Adjusted
Assess mortality and progression to acute myeloid leukemia in myelodysplastic syndrome using the non-age adjusted model
Sponsored
CNS International Prognostic Index in Diffuse Large B-Cell Lymphoma (CNS-IPI)
Estimate risk of CNS relapse/progression in diffuse large B-cell lymphoma
MALT Lymphoma prognosis (MALT-IPI)
Estimate prognosis in MALT lymphoma
Khorana risk score
Estimate risk of chemotherapy-associated thrombosis
CLL BALL Score for Relapsed/Refractory CLL
Sokal Score for CML
Estimate survival in CML
EUTOS Score for Chronic Myelogenous Leukemia (CML)
Predict outcomes after CML treatment, adjusted for tyrosine kinase treatments
CMML CPSS-Mol
Estimate risk of progression to AML in those with CMML using molecular genetics data
International Prognostic Scoring System for Waldenstrom Macroglobulinemia
Estimate prognosis with the IPPSWM
Prognosis Calculator for Relapsed/Refractory DLBCL
Estimate survival in relapsed/refractory DLBCL
MDS Specific Frailty Scale
Improve prognostication with this frailty scale specific to those patients with myelodysplastic syndrome.
International prognostic score for asymptomatic early-stage CLL
Estimate likelihood of treatment requirement in patients with early-stage chronic lymphocytic leukemia
ECOG Score
Assess quality of life and degree of well-being in patients with cancer
Karnofsky Score / Performance Status
Assess quality of life and degree of well-being in patients with cancer
Infectious Disease
Neutrophil to Lymphocyte Ratio (NLR)
Antibiotics
Vancomycin Dosing Based on eGFR (creatinine-cystatin C)
Select an appropriate initial dose and interval for vancomycin taking into account renal function using cystatin C & creatinine
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Clostridium Difficile
Diagnosis of Clostridium Difficile Infection
Based on IDSA guidelines
Treatment of First Episode of Clostridium Difficile
Clinical management algorithm for adults, based on IDSA guidelines
Treatment of Recurrent Episode of Clostridium Difficile
Clinical management algorithm for adults, based on IDSA guidelines
Diagnostic Criteria
Duke Criteria for Endocarditis
Diagnose endocarditis
Jones Criteria for Diagnosis of Rheumatic Fever
Diagnose acute rheumatic fever
Kocher Criteria for Septic Arthritis
Determine risk of septic arthritis in a child with an inflamed hip
CSF WBC Correction In Blood Contaminated CSF
Correction equation for white cell count in setting of traumatic lumbar puncture
Febrile Neutropenia
MASCC Febrile Neutropenia Risk
Assess risk in febrile neutropenia and appropriateness for outpatient management
Absolute Neutrophil Count (ANC)
Determine ANC to assess risk of opportunistic infection
Fever in Infants
Philadelphia Criteria in Febrile Infants
Identify febrile infants aged 29 – 56 days old who are lower risk for serious bacterial infection
Boston Criteria for Febrile Infants
Identify febrile infants aged 28 – 89 days old who are lower risk for serious bacterial infection
Rochester Criteria for Febrile Infants
Identify febrile infants aged ≤ 60 days old who are low-risk for serious bacterial infection
Bacterial Meningitis Score for Children
Risk stratification tool for children with possible bacterial meningitis
Liver
Child Pugh Score
Determine severity and estimate mortality in cirrhosis
Prognosis after TIPSS using MELD Score
MELD Score - Age above 12 years
Scoring system used to rank prioritize candidates for liver transplantation, including MELD-Na used in the OPTN match system
BE3A Score
When to treat HCV in decompensated cirrhosis
REFERENCE BOOK
Screening for Hepatitis C | CTFPHC
Review Canadian Task Force on Preventive Health Care guideline on Hepatitis C screening
Summary
Clinician Summary
Clinician FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
Respiratory Tract Infection
Lund-Mackay Sinusitis Stage
Assess severity of chronic rhinosinusitis and assess response to therapy
Pediatric Strep Score
Pneumonia risk (CURB-65)
Estimate prognosis and determine disposition in community-acquired pneumonia. Not yet validated in COVID-19
Westley Croup Score
Assess croup severity
Pneumonia Severity Index (PORT Score)
Determine need for admission in pneumonia. Not yet validated in COVID-19.
Centor Score (modified) for GAS Pharyngitis
Estimate likelihood of GAS pharyngitis
Canadian Influenza Immunization Guide
Adapted from Immunize Canada
Alberta Croup Severity
Sepsis
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
qSOFA Score in Septic Patients
Predict patients at high-mortality risk from sepsis (not diagnose sepsis)
Tuberculosis
TB Skin Test Interpretation
Determine likelihood of TB based on tuberculin skin test
Medical Administration
Mayo Early Screen for Discharge Planning
Identify patients needing specialized discharge planning services
HOSPITAL Score
Determine risk of avoidable hospital readmission
Worklife Balance
Medical Imaging
Body Imaging
CT Severity Index (Pancreatitis)
Predict complication and mortality rate in pancreatitis, based on CT findings (Balthazar score)
Expected spleen size
Provides upper limit of normal for spleen length and volume by ultrasound relative to body height and gender.
Neuroimaging
ASPECTS: Alberta Stroke Programme Early CT Score for Predicting Outcome of Hyperacute Stroke
Predict outcome and risk of hemorrhage in acute ischemic stroke patients eligible for IV thrombolysis
Spinal Instability Neoplastic Score (SINS)
Determine instability risk in patients with spinal neoplasia
Obstetrical imaging
Due Date by LMP
Pregnancy due date calculator
Due Date by Ultrasound
Determine pregnancy due date using ultrasound results
Gestational Age
Thrombosis imaging
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
PE Clinical Probability
Determine pretest probability of PE to guide workup
PERC Rule for Pulmonary Embolism
Use the PERC rule to rule out PE if no criteria are present and pre-test probability is <15%.
Trauma/MSK imaging
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
Canadian C-Spine Rule
Determine whether cervical spine imaging can be safely avoided
NEXUS C-Spine Criteria
Determine whether cervical spine imaging can be safely avoided
Ottawa Ankle Rules
Does this ankle injury require an x-ray?
Ottawa Knee Rules
Does this knee injury require an x-ray?
NEXUS Chest Decision Instrument for Blunt Chest Trauma
Assess the need for chest imaging after blunt trauma
Mental Health
Addictions
CIWA-Ar
Optimize benzodiazepine treatment of patients alcohol withdrawal
Short Michigan Alcoholism Screening Test-geriatric version The SMAST-G
Assess for problem alcohol drinking in the elderly
Alcohol Use Disorders Identification Test-Concise (AUDIT-C)
Brief screen to detecting heavy alcohol use
Alcohol Use Disorders Identification Test (AUDIT)
Screen for active alcohol abuse or dependence
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Anxiety
GAD-7 Anxiety Scale
Screen for generalized anxiety disorder
Patient Health Questionnaire-4 (PHQ-4)
Ultra-Brief Screening for Anxiety and Depression
CAGE Questionnaire
4 question screening for alcohol problems
Edinburgh Postnatal Depression Scale (EPDS)
10 question screener for postpartum depression
Panic Disorder Severity Scale (PDSS)
7 question scale to grade panic disorder severity
Major Depression Inventory (MDI)
12 question depression severity scale
Post Traumatic Stress Disorder (PCL-C)
17 question self-report for Post Traumatic Stress Disorder
Generalized Anxiety Disorder 2 (GAD-2)
Ultra-brief screening for anxiety disorders
Mood Disorder Questionnaire (MDQ)
15 question self-report to screen for bipolar disorder
Post Traumatic Stress Disorder (PCL-5)
20 questions that assesses the DSM-5 symptoms of PTSD
Primary Care PTSD Screen for DSM-5 (PC-PTSD-5)
A five question screener for PTSD
Adult ADHD Self-Report Scales (ASRS)
6 question scale to screen for adult ADHD
Bipolar
Altman Self-Rating Mania Scale (ASRM)
5 question scale to screen and stage severity of hypomania/mania
Young Mania Rating Scale (YMRS)
11 question scale to grade the severity of mania
Patient Health Questionnaire-4 (PHQ-4)
Ultra-Brief Screening for Anxiety and Depression
Edinburgh Postnatal Depression Scale (EPDS)
10 question screener for postpartum depression
Bipolar Spectrum Diagnostic Scale (BSDS)
20 question screener for bipolar spectrum diagnosis
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
16 question geriatric cognitive screener
Major Depression Inventory (MDI)
12 question depression severity scale
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Generalized Anxiety Disorder 2 (GAD-2)
Ultra-brief screening for anxiety disorders
Mood Disorder Questionnaire (MDQ)
15 question self-report to screen for bipolar disorder
Barnes Akathisia Rating Scale (BARS)
A four-item rating scale for drug-induced akathisia.
Cognition
Anticholinergic Burden Assessment Tool
A tool for finding the ACB Score of commonly prescribed medicines, and for calculating the Anticholinergic Burden for your patient.
Sponsored by Astellas Pharma
Bush-Francis Catatonia Rating Scale (BFCRS)
23 questions to assess the severity of catatonia.
REFERENCE BOOK
Screening for Cognitive Impairment | CTFPHC
Summary
Clinician Summary
Clinician FAQ
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
Depression
Hamilton Depression Rating Scale (HAM-D or HDRS)
Determine severity of depression
Modified SAD PERSONS Scale
Assess depression with the modified SAD PERSONS Scale
Patient Health Questionnaire-9 (PHQ-9)
Screening tool to assist in identifying major depressive disorder
Geriatric Depression Scale
A questionnaire to screen for depression in geriatric populations
Patient Health Questionnaire-2 (PHQ-2)
Ultra-brief screening for depressive disorders
Altman Self-Rating Mania Scale (ASRM)
5 question scale to screen and stage severity of hypomania/mania
Young Mania Rating Scale (YMRS)
11 question scale to grade the severity of mania
Patient Health Questionnaire-4 (PHQ-4)
Ultra-Brief Screening for Anxiety and Depression
CAGE Questionnaire
4 question screening for alcohol problems
Edinburgh Postnatal Depression Scale (EPDS)
10 question screener for postpartum depression
Bipolar Spectrum Diagnostic Scale (BSDS)
20 question screener for bipolar spectrum diagnosis
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
16 question geriatric cognitive screener
Major Depression Inventory (MDI)
12 question depression severity scale
Post Traumatic Stress Disorder (PCL-C)
17 question self-report for Post Traumatic Stress Disorder
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Generalized Anxiety Disorder 2 (GAD-2)
Ultra-brief screening for anxiety disorders
Mood Disorder Questionnaire (MDQ)
15 question self-report to screen for bipolar disorder
Columbia-Suicide Severity Rating Scale (C-SSRS)
5-question suicide risk assessment.
REFERENCE BOOK
Screening for Depression | CTFPHC
Summary
Clinician Summary
Clinician Algorithm & FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
Eating Disorder
Eating Disorder Diagnostic Scale (EDDS)
22 questions to screen for eating disorders
Obsessive Compulsive Disorder
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Eating Disorder Diagnostic Scale (EDDS)
22 questions to screen for eating disorders
Pediatrics
SNAP-IV 26 - Teacher & Parent Rating Scale
Assess children for attention deficit hyperactivity disorder (ADHD)
Adverse Childhood Experience (ACE)
10 question screener for numerous health, social, and behavioral problems.
Post Traumatic Stress
Post Traumatic Stress Disorder (PCL-C)
17 question self-report for Post Traumatic Stress Disorder
Generalized Anxiety Disorder 2 (GAD-2)
Ultra-brief screening for anxiety disorders
Post Traumatic Stress Disorder (PCL-5)
20 questions that assesses the DSM-5 symptoms of PTSD
Primary Care PTSD Screen for DSM-5 (PC-PTSD-5)
A five question screener for PTSD
Psychosis
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)
16 question geriatric cognitive screener
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Barnes Akathisia Rating Scale (BARS)
A four-item rating scale for drug-induced akathisia.
Psychosomatic
Patient Health Questionnaire-15 (PHQ-15)
Somatic Symptom Severity Scale
Who Five Well Being Index (WHO-5)
5 questions to measure mental well-being
Brief Psychiatric Rating Scale (BPRS)
18 clinical questions to assess severity of consolidated symptoms
Sexual Function
Sexual Desire Inventory-2 (SDI-2)
14-item scale for sexual desire
Treatment Side Effects
Abnormal Involuntary Movement Scale (AIMS)
12-item scale to assess severity of dyskinesias
Nephrology
Acute Kidney Injury
APACHE II
Estimate mortality in the critically ill
Contrast Nephropathy Post-PCI
Estimate risk of AKI after percutaneous coronary intervention
Dialysis Risk After Cardiac Surgery (Cleveland Clinic Score by Thakar)
Estimate risk of dialysis after cardiac surgery.
Dialysis Risk After Cardiac Surgery (Mehta)
Estimate the risk of dialysis after cardiac surgery (Mehta model)
Fractional Excretion of Sodium
Differentiate pre-renal AKI from ATN.
Fractional Excretion of Urea
Identify a pre-renal state in patients using diuretics
Sequential Organ Failure Assessment (SOFA)
Document clinical severity in the ICU and predict mortality
Pediatric Renal Angina Index
Predict acute kidney injury in critically ill children
STARRT-AKI Enrollment Criteria
Determine if patients meet criteria for the STARRT-AKI study.
Kinetic eGFR (KeGFR)
Estimate GFR when creatinine is changing acutely (either rising or falling)
PIM2
Paediatric Index of Mortality, revised version
Serious Renal Dysfunction Post-PCI
Assess risk of dialysis or severe increase in creatinine after PCI
CRRT Dosing Calculator
Calculate desired dose of dialysate in CRRT
NCDR AKI and Dialysis Risk after PCI
Estimate risk of AKI and dialysis after PCI
Advanced CKD after AKI Risk Index
Estimate risk of advanced chronic kidney disease after acute kidney injury
Mayo AKI Risk after Primary Total Hip Arthroplasty
Estimate perioperative risk of acute kidney injury
NSAID risk of AKI or hyperkalemia
Calculator to predict risk of AKI or hyperkalemia within 30 days after initiation of prescription NSAIDs in adults 66 years and older.
McMahon Rhabdomyolysis Risk Score
Predict the risk of severe acute kidney injury or mortality in patients with rhabdomyolysis
KDIGO AKI Staging
Classification in acute kidney injury (AKI)
REFERENCE BOOK
KDIGO Clinical Practice Guideline for Acute Kidney Injury
Sponsored
AKI Definition
Prevention and Treatment of AKI
Contrast-induced AKI
Dialysis Interventions for Treatment of AKI
Introduction and Methodology
Introduction
Introduction
Glomerular filtration rate and serum creatinine
Oliguria and anuria
Acute tubular necrosis (ATN)
ARF
RIFLE criteria
AKI: acute kidney injury/impairment
Validation studies using RIFLE
Limitations to current definitions for AKI
Rationale for a guideline on AKI
Summary
Methodology
Introduction
Group member selection and meeting process
Evidence selection, appraisal, and presentation
Outcome selection judgments, values, and preferences
Grading the quality of evidence and the strength of recommendations
SPONSORSHIP
DISCLAIMER
SUPPLEMENTARY MATERIAL
AKI Definition
Definition and classification of AKI
Introduction
Definition of AKI
Staging AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Risk assessment
Introduction
Recommendations and Rationale
Research Recommendations
Supplementary material
Evaluation and general management of patients with and at risk for AKI
Introduction
Recommendations and Rationale
Research recommendations
Supplementary material
Clinical applications
Introduction
Examples of application of AKI definitions
Estimating baseline SCr
Examples of application of AKI stages
Urine output vs. SCr
Timeframe for diagnosis and staging
Clinical judgment
Pseudo-AKI
Atypical AKI
Supplementary material
Diagnostic approach to alterations in kidney function and structure
Definitions of AKI, CKD and AKD
GFR and SCr
GFR/SCr algorithm
Oliguria as a measure of kidney function
Kidney damage
Small kidneys as a marker of kidney damage
Integrated approach to AKI, AKD, and CKD
Sponsorship
Disclaimer
Supplementary material
Prevention and Treatment of AKI
Hemodynamic monitoring and support for prevention and management of AKI
Introduction
Fluids: Recommendations and Rationale
Albumin vs. Saline
Hydroxyethylstarch vs. Saline
Vasopressors: Recommendations and Rationale
Protocolized Hemodynamic Management: Recommendations and Rationale
Protocolized hemodynamic management strategies in septic shock
Goal-directed therapy for hemodynamic support during the perioperative period in high-risk surgical patients
Research Recommendations
Supplementary material
General supportive management of patients with AKI, including management of complications
Overview
Glycemic control and nutritional support
Glycemic control in critical illness: Recommendations and Rationale
Nutritional aspects in the prevention and treatment of critically ill patients with AKI
Total Energy Intake: Recommendations and Rationale
Protein Intake: Recommendations and Rationale
Nutrition route: Recommendations and Rationale
Pediatrics Considerations
Research Recommendations
Supplementary material
The use of diuretics in AKI
Introduction
Recommendations and Rationale
Mannitol
Research Recommendations
Vasodilator therapy: dopamine, fenoldopam, and natriuretic peptides
Dopamine for the prevention or treatment of AKI: Recommendations and Rationale
Fenoldopam for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Natriuretic peptides for the prevention or treatment of AKI: Recommendations and Rationale
Research Recommendations
Supplementary Material
Growth factor intervention
Recombinant Human (rh) IGF-1: Recommendations and Rationale
Erythropoietin
Research Recommendations
Supplementary Material
Adenosine receptor antagonists
Introduction
Recommendations and Rationale
Research Recommendations
Prevention of aminoglycoside- and amphotericin-related AKI
Aminoglycoside nephrotoxicity
Treatment of Infections: Recommendations and Rationale
Patients with Normal Kidney Function in Steady State: Recommendations and Rationale
When Treatment with Multiple Daily Dosing is Used for More than 24 Hours: Recommendations and Rationale
When Treatment with Single-Daily Dosing is Used for More than 48 Hours: Recommendations and Rationale
Topical or Local Applications of Aminoglycosides: Recommendations and Rationale
Research Recommendations
Amphotericin B nephrotoxicity: Recommendations and Rationale
Treatment of Systemic Mycoses or Parasitic Infections: Recommendations and Rationale
Research Recommendations
Other methods of prevention of AKI in the critically ill
On-pump vs. off-pump coronary artery bypass surgery: Recommendations and Rationale
Research Recommendations
N-ACETYLCYSTEINE (NAC): Recommendations and Rationale
NAC in critically ill patients: Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary Material
Contrast-induced AKI
Contrast-induced AKI: definition, epidemiology, and prognosis
Background
Recommendations and Rationale
Epidemiology of CI-AKI
Prognosis of CI-AKI
Research Recommendations
Supplementary Material
Assessment of the population at risk for CI-AKI
Recommendations and Rationale
Risk-factor questionnaire
Urinary protein screening
Other risk factors of CI-AKI
Risk models of CI-AKI
Patients at Increased Risk for CI-AKI: Recommendations and Rationale
Nephrotoxicity of Gd chelates
Nephrogenic systemic fibrosis (NSF)
Supplementary Material
Nonpharmacological prevention strategies of CI-AKI
Introduction
Dose/Volume of Contrast-Media Administration: Recommendations and Rationale
Route of administration of contrast media
Research Recommendations
Selection of a Contrast Agent: Recommendations and Rationale
High-osmolar vs. iso-osmolar or low-osmolar contrast media
Low-osmolar vs. iso-osmolar contrast media
i.a. Iodixanol vs. ioxaglate
i.v. Administration
Research Recommendations
Supplementary Material
Pharmacological prevention strategies of CI-AKI
Fluid Administration: Recommendations and Rationale
Use of oral fluids alone in patients at increased risk of CI-AKI: Recommendations and Rationale
Role of nac in the prevention of CI-AKI: Recommendations and Rationale
Theophylline: Recommendations and Rationale
Fenoldopam: Recommendations and Rationale
Statins in the prevention of CI-AKI
Supplementary Material
Effects of hemodialysis or hemofiltration
Recommendations and Rationale
Sponsorship
Disclaimer
Supplementary material
Dialysis Interventions for Treatment of AKI
Timing of renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Criteria for stopping renal replacement therapy in AKI
Introduction
When to discontinue RRT: Recommendations and Rationale
Use of diuretics: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Anticoagulation
Introduction
How to decide to use anticoagulation: Recommendations and Rationale
Patients without an increased bleeding risk or impaired coagulation and not already receiving effective systemic anticoagulation: Recommendations and Rationale
Patients with increased bleeding risk who are not receiving anticoagulation: Recommendations and Rationale
In patients with heparin-induced thrombocytopenia: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Vascular access for renal replacement therapy in AKI
Introduction
Uncuffed nontunneled dialysis catheter vs a tunneled catheter: Recommendations and Rationale
When choosing a vein for insertion of a dialysis catheter in patients with AKI: Recommendations and Rationale
Using ultrasound guidance for dialysis catheter insertion: Recommendations and Rationale
Obtaining a chest radiograph promptly after placement and before first use of an internal jugular or subclavian dialysis catheter: Recommendations and Rationale
Topical antibiotics: Recommendations and Rationale
Antibiotic locks: Recommendations and Rationale
Pediatric considerations
Research Recommendations
Supplementary material
Dialyzer membranes for renal replacement therapy in AKI
Introduction
Recommendations and Rationale
Research Recommendations
Modality of renal replacement therapy for patients with AKI
Introduction
Complementary therapies in AKI patients: Recommendations and Rationale
Hemodynamically unstable patients: Recommendations and Rationale
AKI patients with acute brain injury or other causes of increased intracranial pressure or generalized brain edema: Recommendations and Rationale
Protocols for decreasing hemodynamic instability with intermittent RRT
Peritoneal dialysis
Pediatric considerations
Research Recommendations
Supplementary material
Buffer solutions for renal replacement therapy in patients with AKI
Introduction
Buffer solution: Recommendations and Rationale
Dialysis fluids and replacement fluids in patients with AKI: Recommendations and Rationale
Research Recommendations
Supplementary material
Dose of renal replacement therapy in AKI
Introduction
Dosing: Recommendations and Rationale
Kt/V and Effluent Volume Rates: Recommendations and Rationale
Additional considerations
Research Recommendations
Sponsorship
Dislcaimer
Supplementary material
Organization and Acknowledgements
Notice
Work Group Membership
KDIGO Board Members
Reference Keys
Abbreviations and Acronyms
Abstract
Foreword
Biographic and Disclosure Information
Acknowledgments
References
Chronic Kidney Disease
Kidney Failure Risk Equation (8 Variable)
Estimate risk of progression to end-stage renal disease in CKD patients using 8 variables.
Kidney Failure Risk Equation (4 Variable)
Estimate risk of progression to end-stage renal disease in CKD patients using age, sex, eGFR and proteinuria with KFRE
Chronic Kidney Disease Management: BC Guidelines
Primary care management of CKD
Supported by Shared Care Committee of BC
Predicting 6 and 12 Month Mortality in CKD patients
Estimate mortality in patients with stage IV or V chronic kidney disease.
Vancomycin Dosing Based on eGFR (creatinine-cystatin C)
Select an appropriate initial dose and interval for vancomycin taking into account renal function using cystatin C & creatinine
Clinical outcomes in CKD with severely decreased GFR
Estimate likelihood of clinical outcomes and their timing in people with severely decreased GFR.
Optimizing Care in Diabetic Kidney Disease
Ensure application of evidence-based care in diabetic kidney disease (DKD)
Sponsored
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
Fluids & Electrolytes
Anion Gap
Calculate anion gap for workup of acid-base disorders
Henderson-Hasselbalch
Osmolal Gap
Detect unmeasured osmoles, such as toxic alcohols
Transtubular K Gradient
Workup hypokalemia and hyperkalemia
Water Deficit in Hypernatremia
Determine water replacement in hypernatremia
Volume of Distribution of Urea
Calcium Correction for Hypoalbuminemia
Adjust serum calcium in the setting of low albumin
Total Body Water (Watson Formula)
Corrected Sodium in Hyperglycemia
As used in the new MELD score, to correct Na in the setting of hyperglycemia
Base Excess
Used in assessing acid-base status
Urine Anion Gap or Urine Net Charge
Use urine electrolytes to differentiate renal tubular acidosis from diarrhea-induced non-anion gap metabolic acidosis
Sodium Correction Rate for Hyponatremia
Rate of fluid administration in correction of hyponatremia
Sodium Deficit in Hyponatremia
Amount of required sodium replenishment for the patient with hyponatremia
Predicting Ionized Hypocalcemia in Critical Care
In critical care patients, estimate the single most likely ionised calcium value--with its surrounding 95% range of likely values--as well as the chance the true value is under 1.10 mM. The reference range for arterial iCa is 1.15-1.29 mM.
Chronic Hyperkalemia Optimization Tool
Optimize care in patients with chronic hyperkalemia
Sponsored
Glomerulonephritis
Membranous Prognosis
Estimate risk of progressive renal dysfunction in membranous nephropathy
SLEDAI-2K
Assess disease activity in lupus
International IgAN Prediction Tool - Adults
Determine prognosis in adults with IgA nephropathy
Body Surface Area Based Dosing
Medication dose adjustment based on body surface area (BSA)
International IgAN Prediction Tool - Pediatrics
Determine prognosis in children in IgA nephropathy
Hemodialysis
Access Recirculation
Calculate dialysis access recirculation
Kt/V from PRU
Quantify hemodialysis adequacy
Kt/V Daugirdas
Quantify hemodialysis adequancy
6-Month Mortality on HD
Estimate 6 month mortality on dialysis using the Cohen model
Home HD Candidacy (MATCH-D)
Assess candidacy for home hemodialysis
Percent Reduction of Urea
Phenytoin Adjustment in Renal Failure
3-Month Mortality in Incident Elderly ESRD Patients
Estimate the risk of early death (at 3 months) in elderly patients starting dialysis.
Predicting 3 Year Survival for Incident Elderly ESRD Patients
Determine appropriateness for transplant referral in elderly patients starting dialysis
Dialysis Duration Needed for Methanol Ingestion
Estimate dialysis duration required for methanol poisoning
Dialysis Duration Needed for Ethylene Glycol Ingestion
Estimate dialysis duration required for ethylene glycol poisoning
Guide Transplant Referral for Incident Dialysis Patients Over 70
Guide renal transplant referral with this mortality estimate for dialysis patients 70 years or older at dialysis start
Hypertension
REFERENCE BOOK
Screening for Hypertension | CTFPHC
Summary
Clinician Summary
Recommendations (PDF)
link ⇲
Systematic Review
link ⇲
Tools/Resources
Clinician Algorithm (PDF)
link ⇲
Lupus Nephritis
SLEDAI-2K
Assess disease activity in lupus
Nephrolithiasis
ROKS - Recurrence Of Kidney Stone (2014)
Predict risk of recurrent kidney stones
ROKS – Recurrence Of Kidney Stone (2018)
Predict the risk of a future symptomatic kidney stone after the last symptomatic stone.
PD
PD Candidacy (MATCH-D)
Assess candidacy for peritoneal dialysis
3-Month Mortality in Incident Elderly ESRD Patients
Estimate the risk of early death (at 3 months) in elderly patients starting dialysis.
Predicting 3 Year Survival for Incident Elderly ESRD Patients
Determine appropriateness for transplant referral in elderly patients starting dialysis
Guide Transplant Referral for Incident Dialysis Patients Over 70
Guide renal transplant referral with this mortality estimate for dialysis patients 70 years or older at dialysis start
REFERENCE BOOK
PD Prescription Management Guide
Sponsored
Introduction
Fundamentals of the Prescription
Getting Started: Patient Pathway to First Prescription
Residual Kidney Function
Volume of Distribution of Urea (V
urea
) Formulas and Tables
Peritoneal Membrane Type
PET Calculations
The Standard Peritoneal Equilibrium Test
The Modified PET
The Process to Develop an Initial Prescription
Overview of the Prescription Management Process
Assessment for Initial Prescription
Preliminary Assessment of Drain Volume
Suggested Timetable for Initial and Subsequent Clearance Measurements
Individualizing the Therapy
Overview
Therapy Optimization
Assumptions on Which Modeling Is Based
Membrane Transport Characteristics and Preferred PD Modality
Individualizing the Therapy
Monitoring the Therapy Long Term
Residual Kidney Function
Volume Control
Assessment of Volume Status
Management of Hypervolemia
Routine Clinic Visit
Caveats About Serum Phosphorus and PD
Overview
Appendix
Weekly Dialysis Clearance
Creatinine Clearance (C
Cr
)
Routine Patient Assessment
Automated Peritoneal Dialysis (APD) Regimens (Examples)
Continuous Ambulatory Peritoneal Dialysis (CAPD) Regimen
International Clinical Practice Guideline Recommendations
EXTRANEAL (Icodextrin) PD Solution, Important Risk Information, References & Contributors
EXTRANEAL (Icodextrin) PD Solution Important Risk Information
References
Contributors
PD Prescription Management Guide
link ⇲
PD Prescription
Body Surface Area
Volume Distribution of Urea
Membrane Transport Type
Residual Kidney Function
REFERENCE BOOK
Access Care and Complications Management
Sponsored
Overview
Disclaimer & Use of the Guide
Catheter Insertion and Care
Preoperative Management
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Perioperative and Intraoperative Management
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Postoperative Management
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Chronic Care of Peritoneal Dialysis Catheter
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Noninfectious Complications
Pericatheter and Subcutaneous Leaks
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Management
References
Peritoneal Catheter Obstruction
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Hernia
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Abdominal Discomfort During Infusion and Drain
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Pneumoperitoneum (Shoulder Pain)
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Hemoperitoneum
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Hydrothorax
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Catheter Adapter Disconnect or Fracture of Peritoneal Catheter
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Infectious Complications: Peritonitis Management
Initial Empiric Management of Peritonitis
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Initial Empiric Management of Peritonitis
Staphyloccocus aureus Peritonitis
Enterococcus Peritonitis
Streptococcus Peritonitis
Pseudomonas aeruginosa Peritonitis
Gram-negative Bacilli Organism Peritonitis
Polymicrobial Peritonitis
Culture-negative Peritonitis
Fungal Peritonitis
Mycobacterium Peritonitis
Peritonitis Terminology
Coagulase-negative Staphylococci
Relapsing and Repeat Peritonitis
References
Disclaimer
Infectious Complications: Management of the Exit-site/Tunnel Infection
Introduction
Introduction
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Diagnosis and Management of Exit-site/Tunnel Infection
References
Disclaimer
Antibiotic Dosing Guidelines
Oral Antibiotics Used in Exit-site and Tunnel Infections
Exit-site Antibiotic Prophylaxis
Intraperitoneal Antibiotic Dosing Recommendations for CAPD Patients
Intermittent Dosing of Antibiotics in Automated Peritoneal Dialysis (APD)
References
Surgical Salvage Procedures for Infectious Complications
Simultaneous Catheter Replacement for Relapsing Peritonitis
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
Exit-Site and Tunnel Infections
Key Assessments
Key Activities
Patient Education
Outcomes Evaluation
References
Appendix
Preoperative and Postoperative PD Catheter Insertion Instructions for Patients
Peritoneal Imaging
Principles of Accurate Peritoneal Dialysis Effluent Sampling and Culturing
Peritoneal Effluent Culture Laboratory Processing
Peritonitis Rate Calculations
Differential Diagnosis of Non-infectious Cloudy Effluent
Providing for a Safe Environment for Peritoneal Dialysis
Normal Bacterial Flora of the Human Body
Preoperative Mapping
Introduction
Preoperative Mapping Using a Catheter Sample
Stencil-Based Preoperative Mapping
Preoperative Mapping for Upper Abdominal and Presternal Catheters
Procedure Day Mapping
References
Calculating Peritonitis Rates: An Example
Author Affiliations
Access Care and Complications Management
link ⇲
REFERENCE BOOK
PD Prescription Quick Reference Guide
Sponsored
PD Prescription
Body Surface Area
Volume Distribution of Urea
Membrane Transport Type
Residual Kidney Function
Disclaimer & Background
Adequacy and Ultrafiltration Goals
Volume of Distribution of Urea
PET Calculations
Assessment for Initial Prescription
Preliminary Assessment of Drain Volume
Individualizing Therapy
Assumptions on which modelling is based
EXTRANEAL (Icodextrin) PD Solution Important Risk Information
References
Peritoneal Dialysis Prescription Management Quick Reference Guide
link ⇲
Pathology
Glomerulosclerosis on Biopsy (2015)
Differentiate glomerulosclerosis from kidney disease rather than aging
International IgAN Prediction Tool - Adults
Determine prognosis in adults with IgA nephropathy
International IgAN Prediction Tool - Pediatrics
Determine prognosis in children in IgA nephropathy
Polycystic Kidney Disease
ADPKD Prognostic Tool using Total Kidney Volume
Estimate risk of progression in Autosomal Dominant Polycystic Kidney Disease
Sponsored by Otsuka Canada Pharmaceutical
PROPKD Score
Predict renal survival in Autosomal Dominant Polycystic Kidney Disease (ADPKD) using genetics
Sponsored by Otsuka Canada Pharmaceutical
ADPKD Prognostic Tool using Kidney Dimensions
Estimate risk of progression in Autosomal Dominant Polycystic Kidney Disease
Sponsored by Otsuka Canada Pharmaceutical
Total Kidney Volume (height-adjusted) Calculator & ADPKD Prognostic Tool using Kidney Dimensions
Estimate risk of progression in Autosomal Dominant Polycystic Kidney Disease using kidney dimensions
Sponsored
ADPKD Prognostic Tool using Total Kidney Volume
Estimate risk of progression in Autosomal Dominant Polycystic Kidney Disease using total kidney volume
Sponsored
REFERENCE BOOK
ADPKD Canadian Expert Consensus
Sponsored by Otsuka Canada Pharmaceutical
Key Messages
Introduction
Genetic Testing in ADPKD
Renal Imaging in ADPKD
Predicting Renal Progression
Methods to Predict Renal Progression
Predicting Progression with the PROPKD Score
Predicting Progression with Genetic Scoring
Predicting Progression with the Mayo Classification
Treatment Options for ADPKD
Non-targeted Options for ADPKD
ADPKD-Specific Treatment Options
References
PROPKD Calculator
Mayo ADPKD Prognostic Tool using Kidney Dimensions
Mayo ADPKD Prognostic Tool using Total Kidney Volume
Thrombotic Microangiopathy
Recognize Thrombotic Microangiopathy
Sponsored Content
Identify Type of Thrombotic Microangiopathy
Sponsored Content
Transplant
Renal Graft Failure at 5-Years, Predicted 1 Year Post Transplant
Estimate the risk of kidney transplant graft failure at 5 years
Renal Graft Failure at 5-Years, Predicted 7 Days Post Transplant
Estimate the risk of kidney transplant graft failure at 5 years
Renal Graft Failure at 5-Years, Predicted at Time of Transplant
Estimate the risk of kidney transplant graft failure at 5 years
Predicting 3 Year Survival for Incident Elderly ESRD Patients
Determine appropriateness for transplant referral in elderly patients starting dialysis
ESRD Risk Tool for Kidney Donor Candidates
15-year and lifetime risk for kidney donors
Guide Transplant Referral for Incident Dialysis Patients Over 70
Guide renal transplant referral with this mortality estimate for dialysis patients 70 years or older at dialysis start
eGFR
CrCl Cockroft-Gault
Estimate creatinine clearance
CrCl from 24h Urine
Calculate creatinine clearance from a 24h urine collection.
Mayo Quadratic eGFR
MDRD eGFR
Calculate eGFR using the MDRD formula
MDRD eGFR (6 Variable)
eGFR using CKD-EPI
Calculate eGFR using the CKD-EPI formula
Schwartz Pediatric Bedside eGFR (2009)
The revised "bedside" pediatric eGFR requires only serum creatinine and height.
Schwartz Pediatric eGFR, Full Model (2009)
The full Schwartz pediatric eGFR calculation requires height, serum creatinine, cystatin C, blood urea nitrogen and gender.
Neurology / Neurosurgery
Arteriovenous Malformation
AVM Rupture Risk
Estimate risk of rupture of an arteriovenous malformation (AVM)
Spetzler-Martin Score
R₂eD AVM Hemorrhage Risk
Estimate risk of hemorrhage in patients with cerebral arteriovenous malformations
Coma/Level of Consciousness
FOUR Score
Glasgow Coma Scale (GCS)
Document level of consciousness.
Pediatric Glasgow Coma Scale
CAM-ICU
Diagnose delirium in the intensive care unit.
The Richmond Agitation Sedation Score (RASS)
Assess level of consciousness in the intensive care unit.
Anticholinergic Burden Assessment Tool
A tool for finding the ACB Score of commonly prescribed medicines, and for calculating the Anticholinergic Burden for your patient.
Sponsored by Astellas Pharma
Glasgow Outcome Scale Extended [GOS-E]
Stratifies patient’s functional outcome after acute brain injury
Bush-Francis Catatonia Rating Scale (BFCRS)
23 questions to assess the severity of catatonia.
SWAP Score for Out of Hospital Cardiac Arrest
Predicts which patients with OHCA will have poor neurologic recovery
Dementia/Neurodegenerative
Diagnosis of Dementia with Lewy Bodies (DLB)
Diagnose patients with dementia with Lewy Bodies based on the 2017 criteria
Diagnosis of Multiple System Atrophy (MSA)
Diagnose Multiple Systems Atrophy based on the 2008 criteria
Dermatome Map
Anterior Dermatome Map
Head and Neck Dermatome Map
Posterior Dermatome Map
Top View Dermatome Map
Functional Outcome
Modified Rankin Scale (mRS)
Erasmus GBS Respiratory Insufficiency Score (EGRIS)
Predict the probability of respiratory insufficiency within the first week of admission, in individual patients with Guillain-Barré syndrome.
Modified Erasmus GBS Outcome Score (EGOS) at hospital admission
Predict probability of being unable to walk independently during follow up in patients with Guillain-Barré syndrome. Score taken at hospital admission.
Modified Erasmus GBS Outcome Score (EGOS) at day 7 of admission
Predict the probability of being unable to walk independently during follow up in patients with Guillain-Barré syndrome. Score taken after 7 days of hospital admission.
Dutch Meningitis Risk Score
The Dutch Meningitis Risk Score is a bedside risk score for unfavorable outcome in adults with bacterial meningitis.
Head & Neck Trauma
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
Canadian C-Spine Rule
Determine whether cervical spine imaging can be safely avoided
NEXUS C-Spine Criteria
Determine whether cervical spine imaging can be safely avoided
Glasgow Outcome Scale Extended [GOS-E]
Stratifies patient’s functional outcome after acute brain injury
Headache
MIDAS (Migraine Disability Assessment)
Measure level of disability in patients with migraines
Intracerebral Hemorrhage
ICH FUNC Score
Predict likelihood of functional independence after intracranial hemorrhage
ICH Score
Estimate mortality after intracerebral hemorrhage
ICH Volume
Blood on MRI
Ischemic Stroke
ABCD² Score
Guide admission in TIA based on ABCD² Score
CHADS2 Score for Atrial Fibrillation
Assess risk of stroke in atrial fibrillation
CHA2DS2-VASc Score for AF
Replacement for CHADS2 for stroke prediction in atrial fibrillation
t-PA Dosing in Acute Stroke
TICI Score
Asymptomatic ICA (Internal Carotid Artery) Stenosis Surgical Risk Stratification
DRAGON Score for Post-TPA Stroke Outcome
The DRAGON Score predicts outcome at 3 months in ischemic stroke patients receiving tPA.
NIH Stroke Scale/Score (NIHSS)
NIH Stroke Scale provides an assessment for stroke severity.
Vascular Quality Initiative (VQI) 30-Day Stroke Risk Index for CEA
Estimate risk of stroke within 30 days after carotid endarterectomy
Vascular Quality Initiative (VQI) 1-Year Mortality Risk Index for CEA
Estimate probability of death within 1 year after carotid endarterectomy
ROSIER scale
Determine which patients are likely to have true stroke vs stroke mimics
ASPECTS: Alberta Stroke Programme Early CT Score for Predicting Outcome of Hyperacute Stroke
Predict outcome and risk of hemorrhage in acute ischemic stroke patients eligible for IV thrombolysis
TIA Prognosis: Risk of Stroke by 90 Days After Presentation
Risk stratify stroke risk within 90 days of TIA presentation
Canadian TIA Score
Estimate 7-day Risk of Stroke or Carotid Revascularization
Movement Disorder
Abnormal Involuntary Movement Scale (AIMS)
12-item scale to assess severity of dyskinesias
Barnes Akathisia Rating Scale (BARS)
A four-item rating scale for drug-induced akathisia.
Multiple Sclerosis & Demyelinating Disease
Multiple Sclerosis: Diagnosis
Diagnose MS using the 2017 McDonald Criteria
PML Risk Stratification in Multiple Sclerosis Patients on Natalizumab
Stratify risk of developing PML in patients with Multiple Sclerosis who are on natalizumab
Primary Progressive Multiple Sclerosis: Diagnosis
Diagnose Primary Progressive MS using the 2017 McDonald Criteria
Neurophysiology
Cerebral Perfusion Pressure
Calculate net pressure gradient causing cerebral blood flow to the brain
Seizure
Fosphenytoin Load
Phenytoin Adjustment in Renal Failure
Seizure vs Syncope
Determine which patients are likely to have seizure versus syncope as the cause of loss of consciousness
2HELPS2B Score
Estimate duration of EEG monitoring needed to detect 95% of seizures
Subarachnoid Hemorrhage
SAH Fisher Grade
SAH Hunt & Hess Scale
Modified Fisher Scale
WFNS SAH Scale
Ottawa SAH Rule
Use the Ottawa SAH Rule to rule out subarachnoid hemorrhage
PHASES Score
Predict risk of rupture for asymptomatic intracranial aneurysms
Thrombotic Microangiopathy
Recognize Thrombotic Microangiopathy
Sponsored Content
Identify Type of Thrombotic Microangiopathy
Sponsored Content
Obstetrics & Gynecology
Bishop Score
Predict whether induction of labor will be required.
Due Date by LMP
Pregnancy due date calculator
Due Date by Ultrasound
Determine pregnancy due date using ultrasound results
Gestational Age
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
Edinburgh Postnatal Depression Scale (EPDS)
10 question screener for postpartum depression
Pregnancy Gestation by LMP and Ultrasound Biometry
Predicts estimated delivery dates and gestational age using LMP and biometry
Cervical Cancer TNM Staging
TNM Staging | AJCC 2017
Sexual Health
Sexual Desire Inventory-2 (SDI-2)
14-item scale for sexual desire
Oncology
Body Surface Area, BMI and Lean Body Weight
BMI and BSA (Mosteller)
Calculate BMI and Body Surface Area using Mosteller formula
BMI and BSA (Du Bois)
Determine body mass index and body surface area using Du Bois method
Body Surface Area Based Dosing
Medication dose adjustment based on body surface area (BSA)
Lean Body Weight (Female)
Calculates estimated patient fat-free body mass in females
Lean Body Weight (Male)
Calculates estimated patient fat-free body mass in males
Breast Cancer
Breast Cancer (Clinical) TNM Staging
cTNM Staging | AJCC 2017
Breast Cancer (Pathological) TNM Staging
pTNM Staging | AJCC 2017
REFERENCE BOOK
Screening for Breast Cancer | CTFPHC
Summary
Clinical Recommendation - Summary
Clinical Recommendation - Complete (CMAJ)
link ⇲
Clinician CBE BSE Recommendation
Systematic Review
link ⇲
Tools/Resources
Patient Algorithm
link ⇲
Patient FAQ
link ⇲
Risks vs Benefits: For ages 40-49
link ⇲
Risks vs Benefits: For ages 50-69
link ⇲
Risks vs Benefits: For ages 70-74
link ⇲
Informational Video
link ⇲
Genitourinary Cancers
Prognosis in Renal Cell Carcinoma (UISS)
Estimate survival in renal cell carcinoma
Renal Cell Carcinoma TNM Staging
TNM Staging | AJCC 2017
Bladder Cancer TNM Staging
TNM Staging | AJCC 2017
Head & Neck Cancer Staging
Mucosal Melanoma
Lip and Oral Cavity Cancer (Clinical) TNM Staging
cTNM Staging | AJCC 2017
Lip and Oral Cavity Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Major Salivary Gland Cancer (Clinical)
cTNM Staging | AJCC 2017
Major Salivary Gland Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Nasopharyngeal Cancer TNM Staging
TNM Staging | AJCC 2017
Hypopharyngeal Cancer (Clinical)
cTNM Staging | AJCC 2017
Hypopharyngeal Cancer (Pathological)
pTNM Staging | AJCC 2017
Maxillary Sinus Cancer (Clinical)
cTNM Staging | AJCC 2017
Maxillary Sinus Cancer (Pathological)
pTNM Staging | AJCC 2017
Nasal Cavity and Ethmoid Sinus Cancer (Pathological)
pTNM Staging | AJCC 2017
Nasal Cavity and Ethmoid Sinus Cancer (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Supraglottis (Pathological)
pTNM Staging | AJCC 2017
Laryngeal Cancer: Supraglottis (Clinical)
cTNM Staging | AJCC 2017
Oropharyngeal (p16-) Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Oropharyngeal (p16-) Cancer TNM Staging (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Glottis (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Glottis (Pathological)
pTNM Staging | AJCC 2017
Laryngeal Cancer: Subglottis (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Subglottis (Pathological)
pTNM Staging | AJCC 2017
Differentiated Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Anaplastic Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Medullary Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Malignant Hematology
CMML Prognostic Scoring Systems (from Spain and Dusseldorf)
Assess risk of progression to AML and early mortality in CMML
Diffuse Large B-Cell Lymphoma Prognosis (R-IPI)
Determine prognosis in diffuse large B-cell lymphoma
Follicular Lymphoma prognosis
Determine prognosis in follicular lymphoma (FLIPI)
Acute GVHD Grading
Determine severity in acute graft versus host disease.
Hodgkin's Disease | Prognosis
Estimate prognosis in Hodgkin's disease.
Hematopoietic cell transplantation - specific comorbidity index (HCT-CI)
MDS Revised - International Prognostic Scoring System (IPSS-R)
Assess mortality and progression to acute myeloid leukemia in myelodysplastic syndrome
Hodgkin's Marrow Involvement
Estimate likelihood of bone marrow involvement in Hodgkin's lymphoma.
MDS International Prognostic Scoring System (IPSS)
Determine prognosis in myelodysplastic sydnrome
Multiple Myeloma Prognosis (ISS)
MASCC Febrile Neutropenia Risk
Assess risk in febrile neutropenia and appropriateness for outpatient management
MDS Anemia - EPO/GCSF Response
Identify those with MDS likely to respond to stem-cell factors.
MDS WHO Classification-based Prognostic Scoring System (WPSS)
Estimate survival and risk of transformation to AML in myelodysplastic syndrome.
MGUS Prognosis
Determine risk of malignant progression to myleoma or lymphoproliferative disorder.
MIPI - Mantle Cell Lymphoma Prognosis
Estimate prognosis in mantle cell lymphoma.
DIPSS Prognosis in Myelofibrosis
Estimate prognosis in myelofibrosis.
Smoldering Multiple Myeloma Prognosis
Determine risk of progression to symptomatic multiple myeloma.
Diffuse Large B-cell Lymphoma Prognosis (IPI24)
Determine prognosis in diffuse large B-cell lymphoma.
Diffuse Large B-cell Lymphoma Prognosis (NCCN-IPI)
Estimate prognosis in diffuse large B-cell lymphoma
DIPSS Plus Score for Prognosis in Myelofibrosis
Estimate prognosis in myelofibrosis.
Multiple Myeloma Prognosis (R-ISS)
Revised international staging system for myeloma
CLL-IPI
The International Prognostic Index for patients with chronic lymphocytic leukemia
MDS Revised - International Prognostic Scoring System (IPSS-R) Non-Age Adjusted
Assess mortality and progression to acute myeloid leukemia in myelodysplastic syndrome using the non-age adjusted model
Sponsored
CNS International Prognostic Index in Diffuse Large B-Cell Lymphoma (CNS-IPI)
Estimate risk of CNS relapse/progression in diffuse large B-cell lymphoma
MALT Lymphoma prognosis (MALT-IPI)
Estimate prognosis in MALT lymphoma
Khorana risk score
Estimate risk of chemotherapy-associated thrombosis
CLL BALL Score for Relapsed/Refractory CLL
Sokal Score for CML
Estimate survival in CML
EUTOS Score for Chronic Myelogenous Leukemia (CML)
Predict outcomes after CML treatment, adjusted for tyrosine kinase treatments
CMML CPSS-Mol
Estimate risk of progression to AML in those with CMML using molecular genetics data
International Prognostic Scoring System for Waldenstrom Macroglobulinemia
Estimate prognosis with the IPPSWM
Absolute Neutrophil Count (ANC)
Determine ANC to assess risk of opportunistic infection
International prognostic score for asymptomatic early-stage CLL
Estimate likelihood of treatment requirement in patients with early-stage chronic lymphocytic leukemia
Karnofsky Score / Performance Status
Assess quality of life and degree of well-being in patients with cancer
Spinal Instability Neoplastic Score (SINS)
Determine instability risk in patients with spinal neoplasia
ECOG Score
Assess quality of life and degree of well-being in patients with cancer
Solid Tumor
Carboplatin AUC Dosing (Calvert)
Brain Metastases Prognostic Index
Estimate prognosis in patients with brain metastases using the graded prognostic assessment
Serious Illness Conversation Guide
Steps to elicit important information from your patients about their goals and values
Khorana risk score
Estimate risk of chemotherapy-associated thrombosis
Lung Cancer TNM Staging
TNM Staging | AJCC 2017
Lip and Oral Cavity Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
HPV-Mediated (p16+) Oropharyngeal Cancer (Clinical)
cTNM Staging | AJCC 2017
HPV-Mediated (p16+) Oropharyngeal Cancer (Pathological)
pTNM Staging | AJCC 2017
Absolute Neutrophil Count (ANC)
Determine ANC to assess risk of opportunistic infection
Colorectal Cancer
TNM Staging | AJCC 2017
Gastric Cancer TNM Staging
TNM Staging | AJCC 2017
Cervical Cancer TNM Staging
TNM Staging | AJCC 2017
Hepatocellular Carcinoma TNM Staging
TNM Staging | AJCC 2017
Esophagus and Esophagogastric Junction Cancers (Squamous Cell Carcinoma)
TNM Staging | AJCC 2017
Esophagus and Esophagogastric Junction Cancers (Adenocarcinoma)
TNM Staging | AJCC 2017
Spinal Instability Neoplastic Score (SINS)
Determine instability risk in patients with spinal neoplasia
ECOG Score
Assess quality of life and degree of well-being in patients with cancer
Karnofsky Score / Performance Status
Assess quality of life and degree of well-being in patients with cancer
Lansky score
Performance score in pediatric patients with cancer
REFERENCE BOOK
Screening for Breast Cancer | CTFPHC
Summary
Clinical Recommendation - Summary
Clinical Recommendation - Complete (CMAJ)
link ⇲
Clinician CBE BSE Recommendation
Systematic Review
link ⇲
Tools/Resources
Patient Algorithm
link ⇲
Patient FAQ
link ⇲
Risks vs Benefits: For ages 40-49
link ⇲
Risks vs Benefits: For ages 50-69
link ⇲
Risks vs Benefits: For ages 70-74
link ⇲
Informational Video
link ⇲
REFERENCE BOOK
Screening for Colorectal Cancer | CTFPHC
Summary
Clinician Recommendations Table
Clinician Summary
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Lung Cancer | CTFPHC
Summary
Clinician Summary
Clinician FAQ
1000-Person Tool
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Prostate Cancer | CTFPHC
Summary
Clinician Summary
Prostate Cancer Infographic
1000-Person Tool
Patient FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
CTFPHC Prostate-Specific Antigen Screening Video
link ⇲
Mike Evans Screening Video
link ⇲
REFERENCE BOOK
Screening for Cervical Cancer | CTFPHC
Summary
Clinical Recommendation - Summary
Clinical Recommendation - Complete (CMAJ)
link ⇲
Systematic Review
link ⇲
Tools/Resources
Clinician Algorithm
link ⇲
Clinician FAQ
link ⇲
Patient Algorithm
link ⇲
Patient FAQ
link ⇲
Orthopedics
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
Canadian C-Spine Rule
Determine whether cervical spine imaging can be safely avoided
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
Pulmonary Embolism Severity Index (PESI)
Predict outcome in patients with pulmonary embolism
NEXUS C-Spine Criteria
Determine whether cervical spine imaging can be safely avoided
Ottawa Ankle Rules
Does this ankle injury require an x-ray?
Ottawa Knee Rules
Does this knee injury require an x-ray?
PE Clinical Probability
Determine pretest probability of PE to guide workup
Mangled Extremity Severity Score (MESS)
Assess limb-salvage potential in trauma to the extremity.
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
Injury Severity Score
Describe severity of traumatic injury
Mayo AKI Risk after Primary Total Hip Arthroplasty
Estimate perioperative risk of acute kidney injury
Pittsburgh Knee Rule
Assist with detection of knee fractures and decision to x-ray
McMahon Rhabdomyolysis Risk Score
Predict the risk of severe acute kidney injury or mortality in patients with rhabdomyolysis
Kocher Criteria for Septic Arthritis
Determine risk of septic arthritis in a child with an inflamed hip
Spinal Instability Neoplastic Score (SINS)
Determine instability risk in patients with spinal neoplasia
Otolaryngology (ENT)
General Otolaryngology
Lund-Mackay Sinusitis Stage
Assess severity of chronic rhinosinusitis and assess response to therapy
Modified Strep Score
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
Attia Criteria for Evaluation of Pharyngitis
Estimate likelihood of Streptococcal pharyngitis as the etiology for sore throat
Wullstein Classification of Tympanoplasty
Sadé Grading System of Atelectasis
Bellucci Classification
House Brackmann
Head & Neck Cancer Staging
Mucosal Melanoma
Lip and Oral Cavity Cancer (Clinical) TNM Staging
cTNM Staging | AJCC 2017
Lip and Oral Cavity Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Major Salivary Gland Cancer (Clinical)
cTNM Staging | AJCC 2017
Major Salivary Gland Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Nasopharyngeal Cancer TNM Staging
TNM Staging | AJCC 2017
HPV-Mediated (p16+) Oropharyngeal Cancer (Clinical)
cTNM Staging | AJCC 2017
HPV-Mediated (p16+) Oropharyngeal Cancer (Pathological)
pTNM Staging | AJCC 2017
Hypopharyngeal Cancer (Clinical)
cTNM Staging | AJCC 2017
Hypopharyngeal Cancer (Pathological)
pTNM Staging | AJCC 2017
Maxillary Sinus Cancer (Clinical)
cTNM Staging | AJCC 2017
Maxillary Sinus Cancer (Pathological)
pTNM Staging | AJCC 2017
Nasal Cavity and Ethmoid Sinus Cancer (Pathological)
pTNM Staging | AJCC 2017
Nasal Cavity and Ethmoid Sinus Cancer (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Supraglottis (Pathological)
pTNM Staging | AJCC 2017
Laryngeal Cancer: Supraglottis (Clinical)
cTNM Staging | AJCC 2017
Oropharyngeal (p16-) Cancer TNM Staging (Pathological)
pTNM Staging | AJCC 2017
Oropharyngeal (p16-) Cancer TNM Staging (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Glottis (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Glottis (Pathological)
pTNM Staging | AJCC 2017
Laryngeal Cancer: Subglottis (Clinical)
cTNM Staging | AJCC 2017
Laryngeal Cancer: Subglottis (Pathological)
pTNM Staging | AJCC 2017
Differentiated Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Anaplastic Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Medullary Thyroid Cancer TNM Staging
TNM Staging | AJCC 2017
Pathology & Lab Medicine
Glomerulosclerosis on Biopsy (2015)
Differentiate glomerulosclerosis from kidney disease rather than aging
eGFR using CKD-EPI
Calculate eGFR using the CKD-EPI formula
Calcium Correction for Hypoalbuminemia
Adjust serum calcium in the setting of low albumin
Expected spleen size
Provides upper limit of normal for spleen length and volume by ultrasound relative to body height and gender.
REFERENCE BOOK
Guidance on Autopsy in COVID-19 with FAQ
What Are the Appropriate Collection Procedures If an Autopsy Is Performed for a Suspected Coronavirus Disease 2019 (COVID-19) Case?
What Are the Appropriate Collection Procedures If an Autopsy Is Not Performed for a Suspected Coronavirus Disease 2019 (COVID-19) Case?
What Are the Appropriate Collection Procedures If an Autopsy Is Performed for a Confirmed Coronavirus Disease 2019 (COVID-19) Case?
What Are the Personal Protective Equipment Recommendations for Autopsies on Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) Decedents?
What General Precautions Should Be Taken When Performing an Autopsy on Coronavirus Disease 2019 (COVID-19) Decedents?
What Are Recommended Collection Procedures for Coronavirus Disease 2019 (COVID-19) Postmortem Specimens?
What Are Recommended Practices for Transportation of Human Remains for Coronavirus Disease 2019 (COVID-19) Decedents?
References
Pediatrics
General Pediatrics
PELD Score - Age Younger Than 12 years
PELD (Pediatric End-Stage Liver Disease) is used for liver allocation in the OPTN match system
Schwartz Pediatric Bedside eGFR (2009)
The revised "bedside" pediatric eGFR requires only serum creatinine and height.
Schwartz Pediatric eGFR, Full Model (2009)
The full Schwartz pediatric eGFR calculation requires height, serum creatinine, cystatin C, blood urea nitrogen and gender.
Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT 2.1)
9 question screener for substance use in adolescents
PRAM Score for Pediatric Asthma Exacerbation Severity
Assess asthma severity in pediatric patients
Newborn Hyperbilirubinemia Assessment
Predict risk of newborn (GA >35 weeks) developing hyperbilirubinemia and determine follow-up recommendations
Testicular Workup for Ischemia and Suspected Torsion (TWIST) score
Estimate probability of torsion in acute testicular pain
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Newborn Hyperbilirubinemia Rate of Rise
Calculate rate of serum bilirubin rise to determine risk of severe hyperbilirubinemia
Alberta Croup Severity
Lansky score
Performance score in pediatric patients with cancer
REFERENCE BOOK
Tobacco Smoking in Children and Adolescents | CTFPHC
Summary
Clinical Recommendations
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Developmental Delay | CTFPHC
Review Canadian Task Force on Preventive Health Care guideline on screening for developmental delay
Summary
Clinician Summary
Clinician FAQ
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Obesity in Children | CTFPHC
Summary
Clinician Summary
Clinician Recommendation Table
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Diagnosis and Management of Congenital Diaphragmatic Hernia (CDH): A Clinical Practice Guideline
Key Points
Abridged Recommendations Part 1
Abridged Recommendations Part 2
Podcast
link ⇲
Clinical Practice Guideline
link ⇲
Growth
CDC Height for Age Percentiles for Boys (2 - 20 years)
Calculate Z-score and percentile
CDC Height for Age Percentiles for Girls (2 - 20 years)
Calculate Z-score and percentile
CDC Weight for Age Percentiles for Boys (2-20 years)
Calculate Z-score and percentile
CDC Weight for Age Percentiles for Girls (2 - 20 years)
Calculate Z-score and percentile
CDC Weight for Height Percentiles for Girls (77-121 cm tall)
Calculate Z-score and percentile
CDC/NCHS Infant Weight for Age Percentiles (<36 months)
Calculate Z-score and percentile
CDC Weight for Height Percentiles for Boys (77-121 cm tall)
Calculate Z-score and percentile
CDC/NCHS Infant Length for Age Percentiles (<36 months)
Calculate Z-score and percentile
CDC/NCHS Infant Weight for Length Percentiles (< 36 months)
Calculate Z-score and percentile
CDC/NCHS Infant Head Circumference for Age Percentiles (<36 months)
Calculate Z-score and percentile
Infectious Disease
Modified Strep Score
Pediatric Strep Score
Westley Croup Score
Assess croup severity
Centor Score (modified) for GAS Pharyngitis
Estimate likelihood of GAS pharyngitis
Philadelphia Criteria in Febrile Infants
Identify febrile infants aged 29 – 56 days old who are lower risk for serious bacterial infection
Boston Criteria for Febrile Infants
Identify febrile infants aged 28 – 89 days old who are lower risk for serious bacterial infection
Rochester Criteria for Febrile Infants
Identify febrile infants aged ≤ 60 days old who are low-risk for serious bacterial infection
Kocher Criteria for Septic Arthritis
Determine risk of septic arthritis in a child with an inflamed hip
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Mental Health
SNAP-IV 26 - Teacher & Parent Rating Scale
Assess children for attention deficit hyperactivity disorder (ADHD)
Trauma/Critical Care
APGAR
Rapid newborn clinical assessment
Pediatric Endotracheal Tube Size
Pediatric Glasgow Coma Scale
PIM2
Paediatric Index of Mortality, revised version
PCDAI
Pediatric Crohn's Disease Activity Index
PECARN Rule for Pediatric Head Injury < 2 years old
Assess the need for neuroimaging in pediatric head trauma
PECARN Rule for Pediatric Head Injury ≥ 2 years old
Assess the need for neuroimaging in pediatric head trauma
Physical Medicine and Rehabilitation
ICH FUNC Score
Predict likelihood of functional independence after intracranial hemorrhage
Disability Rating Scale (DRS)
Modified Ashworth Scale (MAS)
National Pressure Ulcer Advisory Panel Staging System (NPUAP)
DRAGON Score for Post-TPA Stroke Outcome
The DRAGON Score predicts outcome at 3 months in ischemic stroke patients receiving tPA.
Mobilization of Hospitalized Patients with COPD Exacerbation (AECOPD-MOB)
Physiotherapy
Mobilization of Hospitalized Patients with COPD Exacerbation (AECOPD-MOB)
Preventive Medicine
ACC/AHA CV Risk Calculator (2013)
Estimate 10-year risk for atherosclerotic cardiovascular disease
Adverse Childhood Experience (ACE)
10 question screener for numerous health, social, and behavioral problems.
REFERENCE BOOK
Screening for Breast Cancer | CTFPHC
Summary
Clinical Recommendation - Summary
Clinical Recommendation - Complete (CMAJ)
link ⇲
Clinician CBE BSE Recommendation
Systematic Review
link ⇲
Tools/Resources
Patient Algorithm
link ⇲
Patient FAQ
link ⇲
Risks vs Benefits: For ages 40-49
link ⇲
Risks vs Benefits: For ages 50-69
link ⇲
Risks vs Benefits: For ages 70-74
link ⇲
Informational Video
link ⇲
REFERENCE BOOK
Screening for Cervical Cancer | CTFPHC
Summary
Clinical Recommendation - Summary
Clinical Recommendation - Complete (CMAJ)
link ⇲
Systematic Review
link ⇲
Tools/Resources
Clinician Algorithm
link ⇲
Clinician FAQ
link ⇲
Patient Algorithm
link ⇲
Patient FAQ
link ⇲
REFERENCE BOOK
Screening for Hypertension | CTFPHC
Summary
Clinician Summary
Recommendations (PDF)
link ⇲
Systematic Review
link ⇲
Tools/Resources
Clinician Algorithm (PDF)
link ⇲
REFERENCE BOOK
Screening for Type 2 Diabetes | CTFPHC
Summary
Clinician Summary
Recommendations (CMAJ)
link ⇲
Systematic Review
link ⇲
Tools/Resources
FINDRISC Diabetes Risk Calculator
Clinician FAQ
link ⇲
Patient FAQ
link ⇲
REFERENCE BOOK
Tobacco Smoking in Children and Adolescents | CTFPHC
Summary
Clinical Recommendations
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Colorectal Cancer | CTFPHC
Summary
Clinician Recommendations Table
Clinician Summary
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Cognitive Impairment | CTFPHC
Summary
Clinician Summary
Clinician FAQ
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Depression | CTFPHC
Summary
Clinician Summary
Clinician Algorithm & FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
REFERENCE BOOK
Screening for Developmental Delay | CTFPHC
Review Canadian Task Force on Preventive Health Care guideline on screening for developmental delay
Summary
Clinician Summary
Clinician FAQ
Clinical Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Lung Cancer | CTFPHC
Summary
Clinician Summary
Clinician FAQ
1000-Person Tool
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Obesity in Adults | CTFPHC
Summary
Clinician Summary
Clinician FAQ
Clinician Algorithm - Calculator
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Obesity in Children | CTFPHC
Summary
Clinician Summary
Clinician Recommendation Table
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Pelvic Exam | CTFPHC
Summary
Clinician Recommendations - Full (Annals of Internal Medicine)
link ⇲
REFERENCE BOOK
Screening for Prostate Cancer | CTFPHC
Summary
Clinician Summary
Prostate Cancer Infographic
1000-Person Tool
Patient FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
CTFPHC Prostate-Specific Antigen Screening Video
link ⇲
Mike Evans Screening Video
link ⇲
REFERENCE BOOK
Screening for Hepatitis C | CTFPHC
Review Canadian Task Force on Preventive Health Care guideline on Hepatitis C screening
Summary
Clinician Summary
Clinician FAQ
Clinician Recommendations - Full (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Screening for Abdominal Aortic Aneurysm | CTFPHC
Summary
Clinician Summary
Clinician Recommendation Table
1000-Person Tool
Clinician Recommendation - Complete (CMAJ)
link ⇲
CMAJ Author Podcast
link ⇲
REFERENCE BOOK
Impaired Vision | CTFPHC
Summary of Recommendations for Clinicians and Policy-Makers
Clinician Summary
Clinician FAQ
Podcast
link ⇲
Clinician Recommendation - Complete (CMAJ)
link ⇲
Guideline Presentation
link ⇲
REFERENCE BOOK
Screening for Asymptomatic Bacteriuria in Pregnancy | CTFPHC
Summary of Recommendations for Clinicians and Policy-Makers
Clinician Summary
Clinician FAQ
Podcast
link ⇲
Clinician Recommendation - Complete (CMAJ)
link ⇲
Guideline Presentation
link ⇲
REFERENCE BOOK
Screening Adults for Asymptomatic Thyroid Dysfunction in Primary Care | CTFPHC
Clinician FAQ
Summary of recommendations
Podcast
link ⇲
Full Guidelines
link ⇲
REFERENCE BOOK
Screening for Esophageal Adenocarcinoma in Patients with Chronic Rastroesophageal Reflux Disease | CTFPHC
Summary of Recommendations for Clinicians and Policy-Makers
Clinician Summary
Clinician FAQ
Podcast
link ⇲
Clinician Recommendation - Complete (CMAJ)
link ⇲
Guideline Presentation
link ⇲
Respirology
Asthma & COPD
BODE Index for COPD
Estimate prognosis in COPD
Corticosteroid Equivalence
Determine equivalent dosage of corticosteroid
Peak Expiratory Flow Prediction
Ottawa chronic obstructive pulmonary disease risk scale (OCRS)
Guide admission vs discharge in COPD exacerbation
Risk of Occupational Asthma due to High-Molecular Weight Agents
Estimate the likelihood of occupational asthma in subjects exposed to high-molecular weight agents
DVT/PE
DVT Clinical Probability (Well's)
Determine pretest probability of DVT to guide workup
Pulmonary Embolism Severity Index (PESI)
Predict outcome in patients with pulmonary embolism
PE Clinical Probability
Determine pretest probability of PE to guide workup
PERC Rule for Pulmonary Embolism
Use the PERC rule to rule out PE if no criteria are present and pre-test probability is <15%.
sPESI | simplified Pulmonary Embolism Severity Index
Estimate risk of 30-day mortality in patients with acute PE
Hestia Criteria for Outpatient Management of Pulmonary Embolism
Identify patients with acute PE who may be appropriate for outpatient management
General Respirology
A-a Gradient
Used to determine cause of hypoxemia
Mortality in IPF (GAP Index)
Estimate mortality in idiopathic pulmonary fibrosis
In-flight PaO₂ (based on ABG)
In-flight PaO₂ (ABG & PFT)
Nasal Cannula FiO₂ Estimation
PaO₂:FiO₂ Ratio
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
VQI: Respiratory Adverse Event Risk Post Vascular Surgery
Estimate the risk of pneumonia or respiratory failure after vascular surgery
TB Skin Test Interpretation
Determine likelihood of TB based on tuberculin skin test
Erasmus GBS Respiratory Insufficiency Score (EGRIS)
Predict the probability of respiratory insufficiency within the first week of admission, in individual patients with Guillain-Barré syndrome.
Light's Criteria
Determine whether a pleural effusion is exudative or transudative
ROX Index to Predict Risk of Intubation
Predict risk of intubation at 2, 6 and 12 hours in hypoxemic respiratory failure. Not yet validated for COVID-19
ProVent 14 Score for prolonged mechanical ventilation
Determine risk of 1-year mortality after prolonged mechanical ventilation
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
ARISCAT Score
Risk calculator for postoperative pulmonary complications
Lung Cancer
Solitary Pulmonary Nodule Malignancy Risk
Workup a solitary pulmonary nodule
Lung Cancer TNM Staging
TNM Staging | AJCC 2017
Pneumonia
Pneumonia risk (CURB-65)
Estimate prognosis and determine disposition in community-acquired pneumonia. Not yet validated in COVID-19
Pneumonia Severity Index (PORT Score)
Determine need for admission in pneumonia. Not yet validated in COVID-19.
Sleep
Epworth Sleepiness Scale
Screen for excessive sleepiness or follow response to treatment for a sleep disorder
STOP-BANG Score for Obstructive Sleep Apnea
Screen for obstructive sleep apnea
Pittsburgh Sleep Quality Index (PSQI)
Measure your patient's sleep quality
Rheumatology
Ankylosing Spondylitis
ASDAS-CRP (Ankylosing Spondylitis Disease Activity Score)
Assess disease activity in Ankylosing Spondylitis.
ASDAS-ESR (Ankylosing Spondylitis Disease Activity Score)
Assess disease activity in Ankylosing Spondylitis.
BASDAI
Assess disease activity in Ankylosing Spondylitis
Diagnostic criteria
Adult Onset Still's Disease, Diagnostic Criteria
Diagnose Adult Onset Still's Disease.
Jones Criteria for Diagnosis of Rheumatic Fever
Diagnose acute rheumatic fever
Polymyalgia Rheumatica (2012 EULAR/ACR Provisional Criteria)
Review EULAR/ACR criteria for polymyalgia rheumatica
Scleroderma/Systemic Sclerosis (2013 EULAR/ACR Criteria)
Review EULAR/ACR criteria for scleroderma
RPDAI (Relapsing Polychondritis Disease Activity Index)
Assess disease activity in relapsing polychondritis.
Kocher Criteria for Septic Arthritis
Determine risk of septic arthritis in a child with an inflamed hip
Acute Gout Diagnosis Rule
Clinical decision tool to assist in the diagnosis of acute gout
Behcet’s Syndrome International Study Group Criteria
Diagnose Behcet’s disease
Lupus
SLICC SLE Criteria
The SLICC criteria are validated criteria for making the diagnosis of lupus.
SLEDAI-2K
Assess disease activity in lupus
SLICC/ACR Damage Index
Measure accumulated damage since onset of lupus
Rheumatoid Arthritis
Simplified Disease Activity Index for RA (SDAI)
Assess disease activity in rheumatoid arthritis.
DAS28-CRP for Rheumatoid Arthritis
Assess disease activity in rheumatoid arthritis.
DAS28-ESR for Rheumatoid Arthritis
Assess disease activity in rheumatoid arthritis.
Clinical Disease Activity Index for RA (CDAI)
Assess disease activity in rheumatoid arthritis, without requiring lab work.
Vasculitis
Vasculitis Damage Index (VDI)
Document any organ damage that has occurred in patients since the onset of vasculitis
Surgery
Breast Cancer
Breast Cancer (Clinical) TNM Staging
cTNM Staging | AJCC 2017
Breast Cancer (Pathological) TNM Staging
pTNM Staging | AJCC 2017
Inflammatory Bowel Disease
Crohn's Disease Activity Index (CDAI)
Assess disease activity in Crohn's disease
Mayo Score for Ulcerative Colitis Activity
Assess disease activity in ulcerative colitis
Preoperative Assessment
Gupta Perioperative Cardiac Risk
Determine peri-operative risk for a wide variety of surgeries
Postoperative Respiratory Failure Risk Calculator
Estimate risk of postoperative respiratory failure
Geriatric-Sensitive Perioperative Cardiac Risk Index | GSCRI
Estimate risk of perioperative myocardial infarction or cardiac arrest in patients over 65
ASA Physical Status
Classification system for assessing the fitness of patients before surgery
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
VISION perioperative risk using NT-proBNP
Predict risk of MI, vascular death, and all-cause death in patients having non-cardiac surgery
Surgical Diagnosis & Management
Alvarado Score for Acute Appendicitis
Diagnose appendicitis
Surgical Apgar Score
Assess surgical risk of complications or death at 30 days, as assessed in the post-operative period.
Modified Marshall Score
A definition of organ failure in acute pancreatitis
Modified Glasgow Imrie Severity Criteria for Acute Pancreatitis
Predict outcome in acute pancreatitis
PEN-FAST - Penicillin Allergy Risk Tool
Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.
Trauma
Canadian CT Head Rule
Determine which minor head injury patients need head CT imaging
Glasgow Coma Scale (GCS)
Document level of consciousness.
NEXUS C-Spine Criteria
Determine whether cervical spine imaging can be safely avoided
Ottawa Knee Rules
Does this knee injury require an x-ray?
Parkland Formula
Manage IV fluids required in burns
Mangled Extremity Severity Score (MESS)
Assess limb-salvage potential in trauma to the extremity.
NEXUS Chest Decision Instrument for Blunt Chest Trauma
Assess the need for chest imaging after blunt trauma
Injury Severity Score
Describe severity of traumatic injury
WHO Surgical Safety Checklist
Before Induction of Anaesthesia
Reduce peri-operative death with the WHO Surgical Safety Checklist - 1st step.
Before Patient Leaves OR
Last step in the surgical safety checklist
Before Skin Incision
2nd step in the surgical safety checklist
Transplant
Cardiac
Predicted Heart Mass Calculator (PHM)
Estimate donor/recipient heart mass for optimal cardiac transplant sizing
Liver
PELD Score - Age Younger Than 12 years
PELD (Pediatric End-Stage Liver Disease) is used for liver allocation in the OPTN match system
Alcohol Relapse Risk after Liver Transplant
MELD Score - Age above 12 years
Scoring system used to rank prioritize candidates for liver transplantation, including MELD-Na used in the OPTN match system
UKELD Score
The United Kingdom Model for End-Stage Liver Disease (UKELD) predicts prognosis in chronic liver disease and can be used to prioritize for liver transplantation
Preoperative Assessment
Gupta Perioperative Cardiac Risk
Determine peri-operative risk for a wide variety of surgeries